scholarly journals Leukemic Cells “Gas Up” Leaky Bone Marrow Blood Vessels

Cancer Cell ◽  
2017 ◽  
Vol 32 (3) ◽  
pp. 276-278 ◽  
Author(s):  
Tomer Itkin ◽  
Shahin Rafii
Keyword(s):  
Bone Marrow ◽  
Blood Vessels ◽  
Leukemic Cells ◽  
Bone Marrow Blood

scholarly journals Distinct bone marrow blood vessels differentially regulate haematopoiesis

Nature ◽  
2016 ◽  
Vol 532 (7599) ◽  
pp. 323-328 ◽  
Author(s):  
Tomer Itkin ◽  
Shiri Gur-Cohen ◽  
Joel A. Spencer ◽  
Amir Schajnovitz ◽  
Saravana K. Ramasamy ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Blood Vessels ◽  
Bone Marrow Blood

scholarly journals Erratum: Corrigendum: Distinct bone marrow blood vessels differentially regulate haematopoiesis

Nature ◽  
2016 ◽  
Vol 538 (7624) ◽  
pp. 274-274 ◽  
Author(s):  
Tomer Itkin ◽  
Shiri Gur-Cohen ◽  
Joel A. Spencer ◽  
Amir Schajnovitz ◽  
Saravana K. Ramasamy ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Blood Vessels ◽  
Bone Marrow Blood

scholarly journals Bone marrow blood vessels: normal and neoplastic niche

2016 ◽  
Author(s):  
Saeid Shahrabi ◽  
Hadi Rezaeeyan ◽  
Ahmad Ahmadzadeh ◽  
Mohammad Shahjahani ◽  
Najmaldin Saki
Keyword(s):  
Bone Marrow ◽  
Blood Vessels ◽  
English Language ◽  
Relevant Literature ◽  
Leukemia Cells ◽  
Chemotherapy Drugs ◽  
Pathological Conditions ◽  
Pubmed Search ◽  
Bone Marrow Blood

Blood vessels are among the most important factors in the transport of materials such as nutrients and oxygen. This study will review the role of blood vessels in normal bone marrow hematopoiesis as well as pathological conditions like leukemia and metastasis. Relevant literature was identified by a Pubmed search (1992-2016) of English-language papers using the terms bone marrow, leukemia, metastasis, and vessel. Given that blood vessels are conduits for the transfer of nutrients, they create a favorable situation for cancer cells and cause their growth and development. On the other hand, blood vessels protect leukemia cells against chemotherapy drugs. Finally, it may be concluded that the vessels are an important factor in the development of malignant diseases.

scholarly journals Intermittent PTH(1-84) is osteoanabolic but not osteoangiogenic and relocates bone marrow blood vessels closer to bone-forming sites

2011 ◽  
Vol 26 (11) ◽  
pp. 2583-2596 ◽  
Author(s):  
Rhonda Prisby ◽  
Alain Guignandon ◽  
Arnaud Vanden-Bossche ◽  
Fabrice Mac-Way ◽  
Marie-Thérèse Linossier ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Blood Vessels ◽  
Intermittent Pth ◽  
Bone Marrow Blood

Bone and Bone Marrow Blood Flow in Blastic Crisis of Chronic Granulocytic Leukaemia

1979 ◽  
Vol 18 (06) ◽  
pp. 290-292 ◽  
Author(s):  
R. Lahtinen ◽  
T. Lahtinen
Keyword(s):  
Bone Marrow ◽  
Cell Proliferation ◽  
Blood Flow ◽  
Proximal Femur ◽  
Blastic Crisis ◽  
Normal Bone ◽  
Chronic Granulocytic Leukaemia ◽  
Washout Curves ◽  
Bone Marrow Blood

SummaryA l33Xe washout method has been used for measuring changes of blood flow in the proximal femur of a patient with the blastic crisis of chronic granulocytic leukaemia. In the hyperplastic phase the blood flow was highly increased and over three times greater than in the hypoplastic phase of the disease and over thirteen times greater than the value in normal bone. The bone circulation and especially the first component of the two-exponential bone washout curves appeared to reflect cell proliferation and neoplastic activity of the whole bone marrow. The method may provide clinically important information in the follow-up of selected haematological diseases.

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