Efficacy of carotid artery stenting on stroke prevention of octogenarians

The superiority of carotid endarterectomy (CEA) plus best medical treatment (BMT) over BMT alone for the management of patients with asymptomatic carotid stenosis is based on randomized controlled trials that recruited patients up to 30 years ago. Best medical treatment has improved considerably since that time with respect to stroke prevention. Furthermore, a new carotid intervention has emerged during the last 2 decades and has gradually become established, that is, carotid artery stenting (CAS). Consequently, the efficacy of current BMT alone needs to be compared not only with CEA plus BMT but also with CAS plus BMT to determine which strategy achieves the optimal stroke prevention rates. This article highlights the purpose of the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) 2 and discusses the issues that CREST-2 will hopefully provide answers to.

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Carotid Artery Stenting Versus Endarterectomy for Stroke Prevention

Journal of the American College of Cardiology ◽

10.1016/j.jacc.2017.02.053 ◽

2017 ◽

Vol 69 (18) ◽

pp. 2266-2275 ◽

Cited By ~ 62

Author(s):

Partha Sardar ◽

Saurav Chatterjee ◽

Herbert D. Aronow ◽

Amartya Kundu ◽

Preethi Ramchand ◽

...

Keyword(s):

Carotid Artery ◽

Stroke Prevention ◽

Carotid Artery Stenting

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Carotid Artery Stenting for Stroke Prevention

Canadian Journal of Cardiology ◽

10.1016/j.cjca.2013.09.030 ◽

2014 ◽

Vol 30 (1) ◽

pp. 22-34 ◽

Cited By ~ 13

Author(s):

Jacqueline Saw

Keyword(s):

Carotid Artery ◽

Stroke Prevention ◽

Carotid Artery Stenting

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Carotid Artery Stenting for Primary and Secondary Stroke Prevention

World Neurosurgery ◽

10.1016/j.wneu.2011.06.019 ◽

2011 ◽

Vol 76 (6) ◽

pp. S40-S59 ◽

Cited By ~ 6

Author(s):

Adnan H. Siddiqui ◽

Sabareesh K. Natarajan ◽

L. Nelson Hopkins ◽

Elad I. Levy

Keyword(s):

Carotid Artery ◽

Stroke Prevention ◽

Carotid Artery Stenting ◽

Secondary Stroke Prevention

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Article Commentary: Late Outcomes of Carotid Artery Stenting: A Critical Review

The American Surgeon ◽

10.1177/000313481107700922 ◽

2011 ◽

Vol 77 (9) ◽

pp. 1117-1130

Author(s):

Charles B. Ross ◽

Andrea E. Yancey ◽

Kelly R. Byrnes ◽

Erik J. Wayne ◽

Amit J. Dwivedi ◽

...

Keyword(s):

Carotid Artery ◽

Carotid Endarterectomy ◽

Critical Review ◽

Stroke Prevention ◽

Carotid Artery Stenting ◽

Occlusive Disease ◽

Potential Influence ◽

Recurrent Stenosis ◽

Carotid Occlusive Disease

The role of carotid artery stenting (CAS) as an alternative to carotid endarterectomy for the treatment of extracranial carotid occlusive disease for stroke prevention continues to evolve. Although technical and device refinements aimed at making CAS safer continue to this day, safety as measured by 30-day and 1-year outcomes has been the primary recipient of regulatory and practice attention. Relatively less emphasis has been placed on the incidence of recurrent stenosis after CAS and the efficacy of CAS in late stroke prevention. Data on late outcomes of CAS, including factors of potential influence, have been emerging and are addressed in this review.

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