scholarly journals Use of QuantiFERON-TB Gold In-tube assay in screening for neutralizing anti-interferon-γ autoantibodies in patients with disseminated nontuberculous mycobacterial infection

2018 ◽  
Vol 24 (2) ◽  
pp. 159-165 ◽  
Author(s):  
U.-I. Wu ◽  
Y.-C. Chuang ◽  
W.-H. Sheng ◽  
H.-Y. Sun ◽  
Y.-T. Jhong ◽  
...  
Keyword(s):  
Mycobacterial Infection ◽  
Interferon Γ ◽  
Nontuberculous Mycobacterial Infection

scholarly journals Interferon-γ Autoantibodies as Predisposing Factor for Nontuberculous Mycobacterial Infection

2016 ◽  
Vol 22 (6) ◽  
pp. 1124-1126 ◽  
Author(s):  
Florent Valour ◽  
Thomas Perpoint ◽  
Agathe Sénéchal ◽  
Xiao-Fei Kong ◽  
Jacinta Bustamante ◽  
...  
Keyword(s):  
Mycobacterial Infection ◽  
Interferon Γ ◽  
Predisposing Factor ◽  
Nontuberculous Mycobacterial Infection

scholarly journals Attenuation of Helper T Cell Capacity for TH1 and TH17 Differentiation in Children With Nontuberculous Mycobacterial Infection

2019 ◽  
Vol 220 (11) ◽  
pp. 1843-1847
Author(s):  
Tiffany A Claeys ◽  
Oscar Rosas Mejia ◽  
Samuel Marshall ◽  
Jason A Jarzembowski ◽  
Don Hayes ◽  
...  
Keyword(s):  
Lymph Node ◽  
Nontuberculous Mycobacteria ◽  
Mycobacterial Infection ◽  
Interferon Γ ◽  
Interleukin 17 ◽  
Th Cells ◽  
Functional Assays ◽  
Nontuberculous Mycobacterial Infection ◽  
Community Controls ◽  
Th17 Differentiation

Abstract Nontuberculous mycobacteria (NTM) infect children with increasing frequency worldwide. Using blood and lymph node tissue from children with NTM lymphadenitis, and uninfected lymph node tissue from community controls, we evaluated helper T (TH) cells in functional assays of TH1/TH17 differentiation and measured the concentration of their associated cytokines at the site of infection. Circulating TH cells from infected children were attenuated in their TH1/TH17 differentiation capacity and expressed less interferon γ and interleukin 17 after polyclonal stimulation. Similar differences were observed at the site of infection, where most cytokine concentrations were unchanged relative to controls. Our data are consistent with a model wherein TH1/TH17 differentiation is attenuated in NTM-infected children.

Disseminated nontuberculous mycobacterial infection in a child with interferon-γ receptor 1 deficiency

2006 ◽  
Vol 165 (7) ◽  
pp. 458-461 ◽  
Author(s):  
Maria N. Tsolia ◽  
Ariane Chapgier ◽  
Polyxeni Taprantzi ◽  
Marina Servitzoglou ◽  
Ioannis Tassios ◽  
...  
Keyword(s):  
Mycobacterial Infection ◽  
Interferon Γ ◽  
Nontuberculous Mycobacterial Infection

scholarly journals Interferon-γ receptor 1 promoter polymorphisms and susceptibility to nontuberculous mycobacterial infection

2002 ◽  
Vol 6 ◽  
pp. S20-S21
Author(s):  
S.D. Rosenzweig ◽  
Alejandro A. Schäffer ◽  
Li Ding ◽  
Rachel Roccia ◽  
James L. Cook ◽  
...  
Keyword(s):  
Mycobacterial Infection ◽  
Interferon Γ ◽  
Promoter Polymorphisms ◽  
Nontuberculous Mycobacterial Infection
Sign in / Sign up

Export Citation Format

Share Document