Can NO-indomethacin counteract the topical gastric toxicity induced by indomethacin interactions with phospholipid bilayers?

2018 ◽  
Vol 169 ◽  
pp. 375-383 ◽  
Author(s):  
Catarina Pereira-Leite ◽  
Cláudia Nunes ◽  
José C. Bozelli ◽  
Shirley Schreier ◽  
Christina S. Kamma-Lorger ◽  
...  
Keyword(s):  
Phospholipid Bilayers ◽  
Gastric Toxicity

First Nano-Infrared Spectroscopy and Imaging Measurements of Single Phospholipid Bilayers

2018 ◽  
Author(s):  
Adrian Cernescu ◽  
Michał Szuwarzyński ◽  
Urszula Kwolek ◽  
Karol Wolski ◽  
Paweł Wydro ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Ir Spectroscopy ◽  
Absorption Band ◽  
Spectral Region ◽  
Near Field ◽  
Phospholipid Bilayers ◽  
Model Systems ◽  
Absorption Bands ◽  
Protein Complement ◽  
20 Nm

<div><div>Scattering-mode Scanning Near-Field Optical Microscopy (sSNOM) allows one to obtain absorption spectra in the mid-IR region for samples as small as 20 nm in size. This configuration has made it possible to measure FTIR spectra of the protein complement of membranes. (Amenabar 2013) We now show that mid-IR sSNOM has the sensitivity required to measure spectra of phospholipids in individual bilayers in the spectral range 800 cm<sup>-1</sup>–1400 cm<sup>-1</sup>. We have observed the main absorption bands of the dipalmitoylphosphatidylcholine headgroups in this spectral region above noise level. We have also mapped the phosphate absorption band at 1070 cm<sup>-1</sup> simultaneously with the AFM topography. We have shown that we could achieve sufficient contrast to discriminate between single and multiple phospholipid bilayers and other structures, such as liposomes. This work opens the way to further research that uses nano-IR spectroscopy to describe the biochemistry of cell membranes and model systems.</div></div><div></div>

scholarly journals The interfacial conformation and transbilayer movement of diacylglycerols in phospholipid bilayers.

1991 ◽  
Vol 266 (2) ◽  
pp. 1177-1186 ◽  
Author(s):  
J A Hamilton ◽  
S P Bhamidipati ◽  
D R Kodali ◽  
D M Small
Keyword(s):  
Phospholipid Bilayers

scholarly journals Binding of vascular anticoagulant alpha (VAC alpha) to planar phospholipid bilayers.

1990 ◽  
Vol 265 (9) ◽  
pp. 4923-4928
Author(s):  
H A Andree ◽  
C P Reutelingsperger ◽  
R Hauptmann ◽  
H C Hemker ◽  
W T Hermens ◽  
...  
Keyword(s):  
Phospholipid Bilayers

NBD-Labeled Cholesterol Analogues in Phospholipid Bilayers: Insights from Molecular Dynamics

2013 ◽  
Vol 117 (44) ◽  
pp. 13731-13742 ◽  
Author(s):  
João R. Robalo ◽  
J. P. Prates Ramalho ◽  
Luís M. S. Loura
Keyword(s):  
Molecular Dynamics ◽  
Phospholipid Bilayers
Sign in / Sign up

Export Citation Format

Share Document