A systematic review on the applications of resting-state fMRI in Parkinson's disease: Does dopamine replacement therapy play a role?

Cortex ◽  
2015 ◽  
Vol 73 ◽  
pp. 80-105 ◽  
Author(s):  
Masoud Tahmasian ◽  
Lisa M. Bettray ◽  
Thilo van Eimeren ◽  
Alexander Drzezga ◽  
Lars Timmermann ◽  
...  
Keyword(s):  
Systematic Review ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Replacement Therapy ◽  
Resting State ◽  
Resting State Fmri ◽  
Dopamine Replacement Therapy

Dopamine dysregulation syndrome in non-Parkinson’s disease patients: a systematic review

2019 ◽  
Vol 27 (5) ◽  
pp. 456-461
Author(s):  
Jodi Cartoon ◽  
Jothi Ramalingam
Keyword(s):  
Systematic Review ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Replacement Therapy ◽  
Diagnostic Criteria ◽  
Case Reports ◽  
Factitious Disorder ◽  
Novelty Seeking ◽  
Dopamine Dysregulation Syndrome ◽  
Dopamine Replacement Therapy

Objectives: To explore the presence of dopamine dysregulation syndrome in non-Parkinson’s disease patients receiving dopamine replacement therapy. Methods: Electronic searches were conducted of Medline, Embase, PsycINFO and PreMedline to capture articles related to dopamine misuse or factitious disorder combined with the presence of dopamine replacement therapy or a non-Parkinson’s disease population. In total, 430 articles were reviewed and studies that addressed dopamine dysregulation syndrome in non-Parkinson’s disease patients were included. Results: Nine case reports were identified. Conclusions: The pathophysiology underlying dopamine dysregulation syndrome has been thoroughly explored with numerous mechanisms posited. What remains unclear is whether dopamine dysregulation syndrome is a phenomenon specific to Parkinson’s disease, as indicated in the proposed diagnostic criteria. A more useful predictor of susceptibility to dopamine dysregulation syndrome may be temperamental traits such as novelty seeking and impulsivity, which overlap with predisposing factors for an addiction disorder.

Hypomania and mania related to dopamine replacement therapy in Parkinson's disease

2014 ◽  
Vol 20 (4) ◽  
pp. 421-427 ◽  
Author(s):  
Franziska Maier ◽  
Josuah Merkl ◽  
Anna L. Ellereit ◽  
Catharine J. Lewis ◽  
Carsten Eggers ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Replacement Therapy ◽  
Dopamine Replacement Therapy

Altered functional topography of the striatum in resting state fMRI in Parkinson's disease

2016 ◽  
Vol 22 ◽  
pp. e156
Author(s):  
Sun Nee Tan ◽  
Yiming Zhang ◽  
Aiping Liu ◽  
Jane Wang ◽  
Martin J. McKeown
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Resting State ◽  
Resting State Fmri ◽  
Functional Topography

scholarly journals “Resting-state fMRI in Parkinson's disease patients with cognitive impairment: A meta-analysis”: Answer to Wang and colleagues

2019 ◽  
Vol 66 ◽  
pp. 253-254
Author(s):  
Amée F. Wolters ◽  
Sjors C.F. van de Weijer ◽  
Albert F.G. Leentjens ◽  
Annelien A. Duits ◽  
Heidi I.L. Jacobs ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Resting State ◽  
Meta Analysis ◽  
Resting State Fmri

Impulse-Control Disorders in Parkinson's Disease

CNS Spectrums ◽  
2008 ◽  
Vol 13 (8) ◽  
pp. 690-698 ◽  
Author(s):  
Joseph M. Ferrara ◽  
Mark Stacy
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Replacement Therapy ◽  
Impulse Control ◽  
Neurodegenerative Disorder ◽  
Psychosocial Impairment ◽  
Olfactory Loss ◽  
Dopamine Replacement Therapy ◽  
Compulsive Behaviors ◽  
Non Motor Symptoms

ABSTRACTParkinson's disease is a neurodegenerative disorder characterized by bradykinesia, rigidity, postural instability, and resting tremor. Increasingly, Parkinson's disease has been associated with a broad spectrum of non-motor symptoms, such as olfactory loss, sleep disorders, autonomic dysfunction, cognitive impairment, psychosis, depression, anxiety, and apathy. In addition, a minority of Parkinson's disease patients develop compulsive behaviors while receiving dopamine-replacement therapy, including medication hoarding, pathological gambling, binge eating, hyperlibidinous behavior, compulsive shopping, and punding. These behaviors may result in psychosocial impairment for patients and therapeutic challenges for clinicians. This article reviews the anatomic substrates, behavioral spectrum, associated factors, and potential treatments for dopamine-replacement therapy-related compulsions in Parkinson's disease.

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