The diagnostic dilemma with the plateau pattern of the time–intensity curve: can the relative apparent diffusion coefficient (rADC) optimise the ADC parameter for differentiating breast lesions?

Author(s):  
W. Tang ◽  
L. Chen ◽  
Z. Jin ◽  
Y. Liang ◽  
W. Zuo ◽  
...  
2015 ◽  
Vol 21 (2) ◽  
pp. 123-127 ◽  
Author(s):  
Luísa Nogueira ◽  
Sofia Brandão ◽  
Eduarda Matos ◽  
Rita Gouveia Nunes ◽  
Hugo Alexandre Ferreira ◽  
...  

2017 ◽  
Vol 59 (8) ◽  
pp. 902-908
Author(s):  
Valentina Cipolla ◽  
Daniele Guerrieri ◽  
Giacomo Bonito ◽  
Simone Celsa ◽  
Carlo de Felice

Background The effect of gadolinium-based contrast agents on diffusion-weighted imaging (DWI) measurements of breast lesions is still not clear. Purpose To investigate gadolinium effects on DWI and apparent diffusion coefficient (ADC) in breast lesions and normal parenchyma with 3 Tesla contrast-enhanced MRI. Material and Methods Pre- and post-contrast DWI (b = 0 and b = 1000 s/mm2) were acquired in 47 patients. Measured ADC values, pre- and post-contrast T2 signal intensity (T2 SI) and contrast-to-noise ratio (CNR) were compared with Wilcoxon signed-rank and rank-sum test ( P < 0.05). Results Post-contrast ADC was reduced only in malignant lesions (−34%), T2 SI was reduced both in malignant (−50%) and benign (−36%) lesions. Post-contrast CNR was reduced in all groups except for benign lesions. Conclusion Gadolinium-based contrast agent causes a significant reduction in ADC values of malignant breast lesions.


2016 ◽  
Vol 33 (3) ◽  
pp. 294-300 ◽  
Author(s):  
Tugba Bostan Bozkurt ◽  
Gonca Koc ◽  
Gulten Sezgin ◽  
Canan Altay ◽  
M. Fazil Gelal ◽  
...  

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