Acute and chronic anemia and short- and long-term outcome of patients with peripheral arterial disease and critical limb ischemia

Purpose Vascular intervention studies generally consider patency and limb salvage as primary outcomes. However, quality of life is increasingly considered an important patient-oriented outcome measurement of vascular interventions. Existing literature was analyzed to determine the effect of different treatments on quality of life for patients suffering from either claudication or critical limb ischemia. Basic methods A review of the literature was undertaken in the Medline library. A search was performed on quality of life in peripheral arterial disease. Results were stratified according to treatment groups. Principal findings Twenty-one articles described quality of life in approximately 4600 patients suffering from peripheral arterial disease. Invasive treatment generally results in better quality of life scores (at a maximum of 2 years of follow-up), compared with non-invasive treatment. In patients with critical limb ischemia, successful revascularization improves quality of life scores. Only one study reported long-term results. Conclusions Increase in quality of life scores can be found for any intervention performed for peripheral arterial disease. However, there is scarce information on long-term quality of life after vascular intervention.

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Long-term outcome of percutaneous transluminal angioplasty in chronic haemodialysis patients with peripheral arterial disease

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfn378 ◽

2008 ◽

Vol 23 (12) ◽

pp. 3996-4001 ◽

Cited By ~ 55

Author(s):

Y. Kumada ◽

T. Aoyama ◽

H. Ishii ◽

M. Tanaka ◽

Y. Kawamura ◽

...

Keyword(s):

Peripheral Arterial Disease ◽

Percutaneous Transluminal Angioplasty ◽

Arterial Disease ◽

Transluminal Angioplasty ◽

Chronic Haemodialysis ◽

Term Outcome ◽

Long Term Outcome ◽

Peripheral Arterial ◽

Percutaneous Transluminal

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Therapeutische Alternativen in der Behandlung schwerer Beinischämien: Erfahrungen bei 190 Patienten an einer Klinischen Abteilung für Angiologie

VASA ◽

10.1024/0301-1526.28.4.271 ◽

1999 ◽

Vol 28 (4) ◽

pp. 271-278 ◽

Cited By ~ 4

Author(s):

Gschwandtner ◽

Minar ◽

Ahmadi ◽

Haumer ◽

Hülsmann ◽

...

Keyword(s):

Critical Limb Ischemia ◽

Limb Ischemia ◽

Vascular Reconstruction ◽

Transluminal Angioplasty ◽

Long Term Results ◽

Term Outcome ◽

Long Term Outcome ◽

Chronic Critical Limb Ischemia ◽

Short And Long Term

Background: Different therapies in consecutive patients (1987–1992) with chronic critical limb ischemia at a department of medical angiology, their short- and long-term outcome were investigated. Patients and methods: 190 patients (112 males, 78 females; age: 67 ± 12 years); 78 in grade II, 112 in grade III according to Rutherford’s classification. Therapeutic regimen: 1. vascular recanalisation by percutaneous transluminal angioplasty [PTA], local or systemic lysis; 2. surgical vascular reconstruction in case of impossibility or failure of catheter procedures; 3. prostanoids and/or antibiotics; 4. local wound treatment including amputations. Results: Vascular recanalisation was attempted in 156/190 (82.1%): PTA in 116/190, surgical vascular reconstruction in 50/190, local in 24/190 and systemic lysis in 8/190 patients. Prostanoids were applied in 89/190 and antibiotics in 73/190 patients. At the time of dismissal 164/190 (86.3%) patients were clinically improved; 11/190 (5.8%) unchanged, 13/190 (6.8%) had undergone major amputations and 2/190 (1.1%) had died. After 2,6 ± 2,2 years 77 of the 141 patients, who were still alive, were reexamined. Among these 77 patients 84.4% were in grade 0 or I, 15.6% in chronic critical limb ischemia. Furthermore 13.0% had been amputated since dismissal. Forty-nine of 190 (25.8%) patients had died 3,2 ± 1,9 years after dismissal from hospital. Conclusion: Catheter techniques, mostly PTA, is possible in the majority of patients with chronic critical limb ischemia. Cooperation with vascular surgeons in case of technical impossibility or failure of catheter recanalisation is mandatory. Such a regimen yields satisfactory short- and long-term results and a low rate of complications.

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