Comparison of permeation enhancing strategies for an oral factor Xa inhibitor using the Caco-2 cell monolayer model

2006 ◽  
Vol 64 (2) ◽  
pp. 229-237 ◽  
Author(s):  
C BRUESEWITZ ◽  
A FUNKE ◽  
U KUHLAND ◽  
T WAGNER ◽  
R LIPP
Keyword(s):  
Cell Monolayer ◽  
Factor Xa ◽  
Factor Xa Inhibitor ◽  
Monolayer Model

Pharmacokinetics, Biotransformation, and Mass Balance of Edoxaban, a Selective, Direct Factor Xa Inhibitor, in Humans

2012 ◽  
Vol 40 (12) ◽  
pp. 2250-2255 ◽  
Author(s):  
Mohinder S. Bathala ◽  
Hiroshi Masumoto ◽  
Toshihiro Oguma ◽  
Ling He ◽  
Chris Lowrie ◽  
...  
Keyword(s):  
Mass Balance ◽  
Factor Xa ◽  
Factor Xa Inhibitor ◽  
Direct Factor

Bioavailability and Safety of the Factor Xa Inhibitor Edoxaban and the Effects of Quinidine in Healthy Subjects

2013 ◽  
Vol 2 (4) ◽  
pp. 358-366 ◽  
Author(s):  
Nobuko Matsushima ◽  
Frank Lee ◽  
Toshiyuki Sato ◽  
Daniel Weiss ◽  
Jeanne Mendell
Keyword(s):  
Healthy Subjects ◽  
Factor Xa ◽  
Factor Xa Inhibitor

Betrixaban – the next direct factor Xa inhibitor?

2016 ◽  
Vol 9 (12) ◽  
pp. 1111-1117 ◽  
Author(s):  
Martin Thoenes ◽  
Joan Minguet ◽  
Karin Bramlage ◽  
Peter Bramlage ◽  
Carmen Ferrero
Keyword(s):  
Factor Xa ◽  
Factor Xa Inhibitor ◽  
Direct Factor

scholarly journals Global Anticoagulant Effects of a Synthetic Anti-Factor Xa Inhibitor (DX-9065a): Implications for Interventional Use

2003 ◽  
Vol 9 (1) ◽  
pp. 1-17 ◽  
Author(s):  
Mahmut Tobu ◽  
Omer Iqbal ◽  
Qing Ma ◽  
Christopher Schultz ◽  
Walter Jeske ◽  
...  
Keyword(s):  
Factor Xa ◽  
Factor Xa Inhibitor

High-dose versus low-dose 4-factor prothrombin complex concentrate for factor Xa inhibitor reversal in intracranial hemorrhage

2021 ◽  
Author(s):  
Spencer Davis ◽  
Stephanie Chauv ◽  
Abby W. Hickman ◽  
Dave S. Collingridge ◽  
Sara Kjerengtroen ◽  
...  
Keyword(s):  
Intracranial Hemorrhage ◽  
Prothrombin Complex Concentrate ◽  
Low Dose ◽  
Factor Xa ◽  
High Dose ◽  
Factor Xa Inhibitor
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