The influence of dopaminergic system in medial prefrontal cortex on ketamine-induced amnesia in passive avoidance task in mice

2016 ◽  
Vol 781 ◽  
pp. 45-52 ◽  
Author(s):  
Maryam Farahmandfar ◽  
Atefeh Bakhtazad ◽  
Ardeshir Akbarabadi ◽  
Mohammad-Reza Zarrindast
Keyword(s):  
Prefrontal Cortex ◽  
Passive Avoidance ◽  
Medial Prefrontal Cortex ◽  
Dopaminergic System ◽  
Passive Avoidance Task ◽  
Avoidance Task

Effects of Large and Small Bilateral Hippocampal Lesions on Two Types of Passive-Avoidance Responses

1965 ◽  
Vol 16 (3_suppl) ◽  
pp. 1277-1290 ◽  
Author(s):  
Daniel R. Snyder ◽  
Robert L. Isaacson
Keyword(s):  
Passive Avoidance ◽  
Food Reward ◽  
Dorsal Hippocampus ◽  
Passive Avoidance Task ◽  
The Other ◽  
Hippocampal Damage ◽  
Avoidance Task ◽  
Small Compartment ◽  
Hippocampal Lesions ◽  
Avoidance Responses

Ten rats with large bilateral hippocampectomies, 10 rats with smaller amounts of damage of the dorsal hippocampus, 10 rats with destruction of postero-lateral neocortex, and 15 normal animals were trained in two types of passive-avoidance situations. One passive-avoidance task required inhibition of drinking while thirsty, the other required an animal to refrain from entering a small compartment after i: had been trained to enter, while hungry, for a food reward. Animals with the largest amounts of hippocampal destruction were impaired in both types of problems. Animals with smaller degrees of hippocampal damage were not different from normal animals in their ability to inhibit licking but were impaired in the other task. Animals with neocortical destruction showed impairment only in the licking situation.

Sign in / Sign up

Export Citation Format

Share Document