Stable desensitization of α7 nicotinic acetylcholine receptors by NS6740 requires interaction with S36 in the orthosteric agonist binding site

2021 ◽  
pp. 174179
Author(s):  
Maria Chiara Pismataro ◽  
Nicole A. Horenstein ◽  
Clare Stokes ◽  
Clelia Dallanoce ◽  
Ganesh A. Thakur ◽  
...  
Keyword(s):  
Binding Site ◽  
Nicotinic Acetylcholine Receptors ◽  
Acetylcholine Receptors ◽  
Agonist Binding ◽  
Nicotinic Acetylcholine ◽  
Α7 Nicotinic Acetylcholine Receptors

scholarly journals How calcium helps α7 nicotinic acetylcholine receptors fulfill their potential

2020 ◽  
Vol 152 (9) ◽  
Author(s):  
Ben Short
Keyword(s):  
Ligand Binding ◽  
Binding Site ◽  
Nicotinic Acetylcholine Receptors ◽  
Acetylcholine Receptors ◽  
Ligand Binding Site ◽  
Nicotinic Acetylcholine ◽  
Channel Opening ◽  
Α7 Nicotinic Acetylcholine Receptors

Study reveals that, at low acetylcholine concentrations, calcium enhances channel opening by binding to a novel motif near the ligand binding site.

scholarly journals [3H]Epibatidine Photolabels Non-equivalent Amino Acids in the Agonist Binding Site ofTorpedoand α4β2 Nicotinic Acetylcholine Receptors

2009 ◽  
Vol 284 (37) ◽  
pp. 24939-24947 ◽  
Author(s):  
Shouryadeep Srivastava ◽  
Ayman K. Hamouda ◽  
Akash Pandhare ◽  
Phaneendra K. Duddempudi ◽  
Mitesh Sanghvi ◽  
...  
Keyword(s):  
Amino Acids ◽  
Binding Site ◽  
Nicotinic Acetylcholine Receptors ◽  
Acetylcholine Receptors ◽  
Agonist Binding ◽  
Nicotinic Acetylcholine

A Novel Agonist Binding Site on Nicotinic Acetylcholine Receptors

1993 ◽  
Vol 13 (1-4) ◽  
pp. 413-436 ◽  
Author(s):  
E. F. R. Pereira ◽  
M. Alkondon ◽  
T. Tano ◽  
N. G. Castro ◽  
M. M. Fróes-Ferra¯o ◽  
...  
Keyword(s):  
Binding Site ◽  
Nicotinic Acetylcholine Receptors ◽  
Acetylcholine Receptors ◽  
Agonist Binding ◽  
Nicotinic Acetylcholine

scholarly journals An Accessory Agonist Binding Site Promotes Activation of α4β2* Nicotinic Acetylcholine Receptors

2015 ◽  
Vol 290 (22) ◽  
pp. 13907-13918 ◽  
Author(s):  
Jingyi Wang ◽  
Alexander Kuryatov ◽  
Aarati Sriram ◽  
Zhuang Jin ◽  
Theodore M. Kamenecka ◽  
...  
Keyword(s):  
Binding Site ◽  
Nicotinic Acetylcholine Receptors ◽  
Acetylcholine Receptors ◽  
Agonist Binding ◽  
Nicotinic Acetylcholine
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