Oncologic safety of breast reconstruction with autologous fat grafting: A systematic review and meta-analysis

2021 ◽  
Author(s):  
Ricardo Tukiama ◽  
René A.C. Vieira ◽  
Ed C.R. Moura ◽  
Ana G.C. Oliveira ◽  
Gil Facina ◽  
...  
Keyword(s):  
Systematic Review ◽  
Breast Reconstruction ◽  
Meta Analysis ◽  
Fat Grafting ◽  
Autologous Fat Grafting ◽  
Autologous Fat

Use of autologous fat grafting for breast reconstruction: A systematic review with meta-analysis of oncological outcomes

2015 ◽  
Vol 68 (2) ◽  
pp. 143-161 ◽  
Author(s):  
Riaz A. Agha ◽  
Alexander J. Fowler ◽  
Christian Herlin ◽  
Tim E.E. Goodacre ◽  
Dennis P. Orgill
Keyword(s):  
Systematic Review ◽  
Breast Reconstruction ◽  
Meta Analysis ◽  
Fat Grafting ◽  
Autologous Fat Grafting ◽  
Autologous Fat ◽  
Oncological Outcomes

scholarly journals Comparison of the Efficacy and Safety of Cell-Assisted Lipotransfer and Platelet-Rich Plasma Assisted Lipotransfer: What Should We Expect from a Systematic Review with Meta-Analysis?

2021 ◽  
Vol 30 ◽  
pp. 096368972198960
Author(s):  
Aizhen Chen ◽  
Li Zhang ◽  
Penghong Chen ◽  
Chaoyu Zhang ◽  
Shijie Tang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Survival Rate ◽  
Platelet Rich Plasma ◽  
Meta Analysis ◽  
Fat Grafting ◽  
Cochrane Library ◽  
Efficacy And Safety ◽  
Autologous Fat Grafting ◽  
Autologous Fat ◽  
Fat Survival

Due to the high absorption rate of traditional autologous fat grafting, cell-assisted lipotransfer (CAL) and platelet-rich plasma (PRP)-assisted lipotransfer were developed. The purpose of this article was to evaluate the efficacy and safety of CAL and PRP in promoting the survival of autologous fat grafting through systematic review and meta-analysis. We searched Pubmed, Cochrane Library, Web of Science, and EMBASE for clinical studies on CAL and PRP-assisted lipotransfer published from January 2010 to January 2020. Then a meta-analysis was performed to assess the efficacy of CAL and PRP-assisted lipotransfer through data analysis of fat survival rate. We also assessed the incidence of complications and multiple operations to analyze their safety. A total of 36 studies (1697 patients) were included in this review. Regardless of the recipient area, CAL and PRP-assisted lipotransfer significantly improved the fat survival rate (CAL vs non-CAL: 71% vs 48%, P < 0.0001; PRP vs non-PRP: 70% vs 40%, P < 0.0001; CAL vs PRP: 71% vs 70%, P = 0.7175). However, in large-volume fat grafting, such as breast reconstruction, both increased the incidence of complications and did not decrease the frequency of multiple operations after lipotransfer. Further prospective studies are needed to evaluate the clinical benefits of CAL and PRP-assisted lipotransfer.

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