Electrochemical and spectral studies on the catalytic oxidation of nitric oxide and nitrite by high-valent manganese porphyrins at an ITO electrode

Abstract Our earlier studies suggested an association between α-thalassemia and hypertension. We postulated that this association might involve trapping of the vasodilator nitric oxide (NO) by hemoglobin (Hb). Hb A has recently been shown to carry NO on its sulfhydryl groups in addition to its hemes. In this report we studied the interaction of purified Hb H as well as Hb A with NO. The number of reactive sulfhydryls were determined spectrophotometrically with bis-dithionitrobenzoate. Spectral studies and nitrosothiol measurements after treatment with NO or nitrosothiols indicated that all eight reactive sulfhydryls of Hb H were capable of binding NO. Hb A, however, was only able to bind and transfer two molecules of NO per tetramer. These findings support the biochemical basis for the association between α-thalassemia and hypertension.

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Selective Oxidation of Nitric Oxide against Nitrite by Oxo-iron(IV) Porphyrin at an ITO Electrode

Chemistry Letters ◽

10.1246/cl.2003.610 ◽

2003 ◽

Vol 32 (7) ◽

pp. 610-611 ◽

Cited By ~ 8

Author(s):

Jianping Lei ◽

Natalia S. Trofimova ◽

Osamu Ikeda

Keyword(s):

Nitric Oxide ◽

Selective Oxidation ◽

Ito Electrode

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Highly Chemoselective and Enantioselective Catalytic Oxidation of Heteroaromatic Sulfides via High-Valent Manganese(IV)–Oxo Cation Radical Oxidizing Intermediates

ACS Catalysis ◽

10.1021/acscatal.7b00968 ◽

2017 ◽

Vol 7 (7) ◽

pp. 4890-4895 ◽

Cited By ~ 15

Author(s):

Wen Dai ◽

Sensen Shang ◽

Ying Lv ◽

Guosong Li ◽

Chunsen Li ◽

...

Keyword(s):

Catalytic Oxidation ◽

Cation Radical ◽

High Valent

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Simultaneous catalytic oxidation of nitric oxide and elemental mercury by single-atom Pd/g-C3N4 catalyst: A DFT study

Molecular Catalysis ◽

10.1016/j.mcat.2020.110901 ◽

2020 ◽

Vol 488 ◽

pp. 110901 ◽

Cited By ~ 2

Author(s):

Xiaoshuo Liu ◽

Zhengyang Gao ◽

Hanyu Huang ◽

Ge Yan ◽

Tianfang Huang ◽

...

Keyword(s):

Nitric Oxide ◽

Catalytic Oxidation ◽

Elemental Mercury ◽

Dft Study ◽

Single Atom

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A Novel Biflavonyloxymethane from Pongamia Pinnata and its Radical Quenching Activity

Natural Product Communications ◽

10.1177/1934578x1100600511 ◽

2011 ◽

Vol 6 (5) ◽

pp. 1934578X1100600 ◽

Cited By ~ 1

Author(s):

Anindita Ghosh ◽

Suvra Mandal ◽

Avijit Banerji ◽

Manoj Kar ◽

Kalyan Hazra ◽

...

Keyword(s):

Nitric Oxide ◽

2D Nmr ◽

Pongamia Pinnata ◽

Spectral Studies ◽

Root Bark

The root bark of Pongamia pinnata Pierre (syn P. glabra Vent.) has afforded a new biflavonyloxymethane, pongabiflavone, along with a known furanoflavone, 3-methoxy-(7, 8, 2″, 3″) furanoflavone. The structure of this new compound was elucidated from extensive spectral studies, including 2D-NMR spectroscopic experiments. The antioxidant, radical quenching activity- superoxide and nitric oxide quenching activities of both pongabiflavone and previously isolated karanjabiflavone have been evaluated which can be a key to cure Psoriasis.

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