Asymmetric reduction of 2-octanone in water/organic solvent biphasic system with Baker's yeast FD-12

2007 ◽  
Vol 40 (5) ◽  
pp. 1305-1311 ◽  
Author(s):  
Yong-Ning Li ◽  
Xian-Ai Shi ◽  
Min-Hua Zong ◽  
Chun Meng ◽  
Ya-Qin Dong ◽  
...  
Keyword(s):  
Organic Solvent ◽  
Asymmetric Reduction ◽  
Baker’S Yeast ◽  
Biphasic System ◽  
Baker's Yeast

ASYMMETRIC REDUCTION OF AROMATIC KETONES BY THE BAKER'S YEAST IN ORGANIC SOLVENT SYSTEMS

2001 ◽  
Vol 31 (10) ◽  
pp. 1521-1526 ◽  
Author(s):  
Xiang Liu ◽  
Tong-Sheng Zhu ◽  
Pei-Dong Sun ◽  
Jian-He Xu
Keyword(s):  
Organic Solvent ◽  
Asymmetric Reduction ◽  
Baker’S Yeast ◽  
Baker's Yeast ◽  
Aromatic Ketones ◽  
Solvent Systems

Baker’s yeast-mediated asymmetric reduction of ethyl 3-oxobutanoate in deep eutectic solvents

2015 ◽  
Vol 50 (11) ◽  
pp. 1788-1792 ◽  
Author(s):  
Marina Cvjetko Bubalo ◽  
Marcelina Mazur ◽  
Kristina Radošević ◽  
Ivana Radojčić Redovniković
Keyword(s):  
Asymmetric Reduction ◽  
Deep Eutectic Solvents ◽  
Baker’S Yeast ◽  
Baker's Yeast

Asymmetric reduction of Z-3-chloro-3-alken-2-ones with fermenting baker's yeast

1986 ◽  
Vol 27 (39) ◽  
pp. 4737-4740 ◽  
Author(s):  
Masanori Utaka ◽  
Satoshi Konishi ◽  
Akira Takeda
Keyword(s):  
Asymmetric Reduction ◽  
Baker’S Yeast ◽  
Baker's Yeast

Synthesis of S-Licarbazepine by Asymmetric Reduction of Oxcarbazepine in Organic Solvent/Phosphate Buffer Biphasic System

2018 ◽  
Vol 921 ◽  
pp. 54-59
Author(s):  
Zhi Hin Ou ◽  
Jia Hui Xu
Keyword(s):  
Organic Solvent ◽  
Bacillus Anthracis ◽  
Efficient Method ◽  
Substrate Concentration ◽  
Phosphate Buffer ◽  
Dibutyl Phthalate ◽  
Cell Concentration ◽  
Asymmetric Reduction ◽  
Volume Ratio ◽  
Biphasic System

S-licarbazepine was synthesized by asymmetric reduction of oxcarbazepine in organic solvent/phosphate buffer biphasic system with Bacillus anthracis CGMCC No.12337 as catalyst. Effects of many factors on reduction were studied. Dibutyl phthalate/phosphate buffer was selected as the optimal biphasic system for reduction. The optimum reduction conditions are as follows: volume ratio of dibutyl phthalate and phosphate buffer 1:1, 30 g/L iospropanol as co-substrate, phosphate buffer pH 5, substrate concentration 7.92 mmol/L, cell concentration 30 g/L, 32°C，180 rpm. The conversion and enantiometric excess of S-licarbazepine reached 97.32% and 99.80%. An efficient method for synthesis of S-licarbazepine was provided.

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