Abdominal Aortic Dissection in a Patient With Autosomal Dominant Polycystic Kidney Disease After Starting Peritoneal Dialysis

Background: Cyst infection is a complication sometimes seen in patients with autosomal dominant polycystic kidney disease (ADPKD) and often shows through a positive blood culture. However, there have been no reports of ADPKD patients whose cyst infection propagate to peritoneal fluid leading to positive peritoneal fluid culture. Case presentation: A 74-year-old Japanese man with ADPKD under peritoneal dialysis (PD) was presented with left flank pain, fever, and chills at our hospital. He did not show any symptoms or signs suggestive of peritonitis. There were no elevated cell counts or polymorphonuclear leucocytes in his PD fluid. There were some complicated cysts found in computed tomography and magnetic resonance imaging examinations. We clinically diagnosed him as having a renal cyst infection rather than PD-related peritonitis. We initiated treatment by administering ceftriaxone with an immediate favorable response. As the possibility of accompanying prostatitis still remained, we switched to intravenous levofloxacin on the second day. On the 10th day, Helicobacter cinaedi was detected in 2 sets of blood culture as well as in PD fluid. We switched back to ceftriaxone and this treatment was entirely successful. Conclusions: This is the first report of H cinaedi cyst infection which propagates to peritoneal fluid in a patient with ADPKD.

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Peritoneal Dialysis for Patients with Autosomal Dominant Polycystic Kidney Disease

Peritoneal Dialysis International ◽

10.3747/pdi.2016.00273 ◽

2017 ◽

Vol 37 (4) ◽

pp. 384-388 ◽

Cited By ~ 6

Author(s):

Sana Khan ◽

Anna Giuliani ◽

Carlo Crepaldi ◽

Claudio Ronco ◽

Mitchell H. Rosner

Keyword(s):

Peritoneal Dialysis ◽

Kidney Disease ◽

Polycystic Kidney Disease ◽

Autosomal Dominant ◽

Disease Patient ◽

Cystic Kidney ◽

Polycystic Kidney ◽

Autosomal Dominant Polycystic Kidney ◽

Stage Renal Disease ◽

End Stage

End-stage renal disease secondary to autosomal dominant poly-cystic kidney (ADPKD) is a common issue worldwide. Peritoneal dialysis (PD) is a reasonable option for renal replacement therapy for these patients and should not be withheld due to concerns that the patient may not tolerate the fluid volumes in the peritoneal cavity. This review covers the existing data on the outcomes and complications associated with the use of PD in the polycystic kidney disease patient. In general, PD is well tolerated and outcomes in ADPKD patients are equivalent to or better than other patient groups.

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Dialysis‐associated acquired cystic kidney disease imitating autosomal dominant polycystic kidney disease in a patient receiving long‐term peritoneal dialysis

Nephrology Dialysis Transplantation ◽

10.1093/ndt/17.3.500 ◽

2002 ◽

Vol 17 (3) ◽

pp. 500-503 ◽

Cited By ~ 7

Author(s):

Daniel Neureiter ◽

Helga Frank ◽

Ulrich Kunzendorf ◽

Rüdiger Waldherr ◽

Kerstin Amann

Keyword(s):

Peritoneal Dialysis ◽

Kidney Disease ◽

Polycystic Kidney Disease ◽

Autosomal Dominant ◽

Cystic Kidney Disease ◽

Cystic Kidney ◽

Polycystic Kidney ◽

Acquired Cystic Kidney Disease ◽

Autosomal Dominant Polycystic Kidney

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Abdominal aortic aneurysms and autosomal dominant polycystic kidney disease.

Journal of the American Society of Nephrology ◽

10.1681/asn.v7112483 ◽

1996 ◽

Vol 7 (11) ◽

pp. 2483-2486

Author(s):

R Torra ◽

C Nicolau ◽

C Badenas ◽

C Brú ◽

L Pérez ◽

...

Keyword(s):

Kidney Disease ◽

Polycystic Kidney Disease ◽

Autosomal Dominant ◽

Abdominal Aortic Aneurysms ◽

Aortic Aneurysms ◽

Aortic Diameter ◽

Polycystic Kidney ◽

Abdominal Aortic ◽

Healthy Family ◽

Autosomal Dominant Polycystic Kidney

Although cases of autosomal dominant polycystic kidney disease (ADPKD) associated with abdominal aortic aneurysm have been repeatedly reported in the literature, no systematic studies of the aortas of these patients have been performed. In the study presented here, a sonographic study of the abdominal aorta in 139 ADPKD patients and in 149 healthy family members was carried out. For both groups, an increase in aortic diameter related to age and sex, (being wider in men than women) was found. In ADPKD patients, neither a wider aortic diameter nor a higher prevalence of abdominal aortic aneurysms could be found in any age group. It was concluded that, although these patients are prone to develop aortic aneurysms because of hypertension and associated connective tissue disorders, the presence of abdominal aortic aneurysms should be questioned as a frequent feature of ADPKD.

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