Recovery of auditory-nerve-fiber spike amplitude under natural excitation conditions

2018 ◽  
Vol 370 ◽  
pp. 248-263
Author(s):  
Adam J. Peterson ◽  
Antoine Huet ◽  
Jérôme Bourien ◽  
Jean-Luc Puel ◽  
Peter Heil
Keyword(s):  
Nerve Fiber ◽  
Auditory Nerve ◽  
Auditory Nerve Fiber ◽  
Spike Amplitude ◽  
Excitation Conditions

scholarly journals Resolution of subcomponents of synaptic release from post-synaptic currents in rat hair-cell/auditory-nerve fiber synapses

2020 ◽  
Author(s):  
Eric D. Young ◽  
Jingjing Sherry Wu ◽  
Mamiko Niwa ◽  
Elisabeth Glowatzki
Keyword(s):  
Hair Cell ◽  
Nerve Fiber ◽  
Hair Cells ◽  
Auditory Nerve ◽  
Neurotransmitter Release ◽  
Auditory Nerve Fiber ◽  
Vesicle Release ◽  
Synaptic Currents ◽  
Synaptic Release

AbstractThe synapse between inner hair cells and auditory nerve fiber dendrites shows large EPSCs, which are either monophasic or multiphasic. Multiquantal or uniquantal flickering release have been proposed to underlie the unusual multiphasic waveforms. Here the nature of multiphasic waveforms is analyzed using EPSCs recorded in vitro in rat afferent dendrites. Spontaneous EPSCs were deconvolved into a sum of presumed release events with monophasic EPSC waveforms. Results include: first, the charge of EPSCs is about the same for multiphasic versus monophasic EPSCs. Second, EPSC amplitudes decline with the number of release events per EPSC. Third, there is no evidence of a mini-EPSC. Most results can be accounted for by versions of either uniquantal or multiquantal release. However, serial neurotransmitter release in multiphasic EPSCs shows properties that are not fully explained by either model, especially that the amplitudes of individual release events is established at the beginning of a multiphasic EPSC, constraining possible models of vesicle release.

Auditory nerve fiber responses following chronic cochlear de-efferentation

1999 ◽  
Vol 406 (1) ◽  
pp. 72-86 ◽  
Author(s):  
Xiang Yang Zheng ◽  
Donald Henderson ◽  
Sandra L. McFadden ◽  
Da Lian Ding ◽  
Richard J. Salvi
Keyword(s):  
Nerve Fiber ◽  
Auditory Nerve ◽  
Auditory Nerve Fiber

Suppression of Auditory-Nerve-Fiber Responses to Off-CF Tones

2011 ◽  
Author(s):  
Maria A. Berezina ◽  
John J. Guinan ◽  
Christopher A. Shera ◽  
Elizabeth S. Olson
Keyword(s):  
Nerve Fiber ◽  
Auditory Nerve ◽  
Auditory Nerve Fiber

Effects of cochlear-synaptopathy inducing moderate noise exposure on auditory-nerve-fiber responses in chinchillas

2017 ◽  
Vol 141 (5) ◽  
pp. 3814-3814 ◽  
Author(s):  
Vijaya Prakash Krishnan Muthaiah ◽  
Michael K. Walls ◽  
Michael G. Heinz
Keyword(s):  
Nerve Fiber ◽  
Auditory Nerve ◽  
Noise Exposure ◽  
Auditory Nerve Fiber
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