Permanent conduction system pacing for congenitally corrected transposition of the great arteries: A Pediatric and Congenital Electrophysiology Society (PACES)/International Society for Adult Congenital Heart Disease (ISACHD) Collaborative Study

Heart Rhythm ◽  
2020 ◽  
Vol 17 (6) ◽  
pp. 991-997 ◽  
Author(s):  
Jeremy P. Moore ◽  
Roberto Gallotti ◽  
Kevin M. Shannon ◽  
Thomas Pilcher ◽  
Jeffrey M. Vinocur ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
International Society ◽  
Congenital Heart ◽  
Adult Congenital Heart Disease ◽  
Collaborative Study ◽  
Conduction System ◽  
Adult Congenital ◽  
Congenitally Corrected Transposition ◽  
Corrected Transposition

Galectin-3 plasma levels in adult congenital heart disease and the pressure overloaded right ventricle: reason matters

2020 ◽  
Vol 14 (13) ◽  
pp. 1197-1205
Author(s):  
Ewa Kowalik ◽  
Beata Kuśmierczyk-Droszcz ◽  
Anna Klisiewicz ◽  
Aleksandra Wróbel ◽  
Anna Lutyńska ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Adult Congenital Heart Disease ◽  
Clinical Status ◽  
Pressure Overload ◽  
Cross Sectional ◽  
Galectin 3 ◽  
Congenitally Corrected Transposition ◽  
Corrected Transposition

Aim: To assess galectin-3 (Gal-3) levels and their relationship with clinical status and right ventricular (RV) performance in adults with RV pressure overload of various mechanisms due to congenital heart disease. Materials & methods: A cross-sectional study was conducted. Patients underwent clinical examination, blood testing and transthoracic echocardiography. Results: The study included 63 patients with congenitally corrected transposition of the great arteries, 41 patients with Eisenmenger syndrome and 20 healthy controls. Gal-3 concentrations were higher in patients compared with controls (7.83 vs 6.11 ng/ml; p = 0.002). Biomarker levels correlated with age, New York Health Association class, N-terminal probrain natriuretic peptide and RV function only in congenitally corrected transposition of the great arteries patients. Conclusion: Gal-3 profile in congenital heart disease patients and pressure-overloaded RV differs according to the cause of pressure overload.

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