Structural characterization and immunomodulatory mechanisms of two novel glucans from Morchella importuna fruiting bodies

2021 ◽  
Author(s):  
Yao Wen ◽  
Sixue Bi ◽  
Xianjing Hu ◽  
Jianing Yang ◽  
Chunlei Li ◽  
...  
Keyword(s):  
Structural Characterization ◽  
Fruiting Bodies ◽  
Morchella Importuna

Structural characterization of a heterogalactan purified from fruiting bodies of Ganoderma atrum

2014 ◽  
Vol 36 ◽  
pp. 339-347 ◽  
Author(s):  
Hui Zhang ◽  
Shao-Ping Nie ◽  
Jun-Yi Yin ◽  
Yuan-Xing Wang ◽  
Ming-Yong Xie
Keyword(s):  
Structural Characterization ◽  
Fruiting Bodies

Structural characterization and antioxidant activity of a polysaccharide from the fruiting bodies of cultured Cordyceps militaris

2007 ◽  
Vol 70 (4) ◽  
pp. 430-436 ◽  
Author(s):  
Rongmin Yu ◽  
Wei Yang ◽  
Liyan Song ◽  
Chunyan Yan ◽  
Zhang Zhang ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Structural Characterization ◽  
Cordyceps Militaris ◽  
Fruiting Bodies

Structural Characterization of Water-Soluble Polysaccharides from the Fruiting Bodies of Lentinus edodes Mushrooms

2012 ◽  
Vol 8 (4) ◽  
pp. 235-241 ◽  
Author(s):  
Irene Palacios ◽  
Eva Guillamon ◽  
Ana Garcia-Lafuente ◽  
Ana Villares
Keyword(s):  
Structural Characterization ◽  
Water Soluble ◽  
Lentinus Edodes ◽  
Fruiting Bodies

scholarly journals Induction of Apoptosis in HeLa Cells by a Novel Peptide from Fruiting Bodies of Morchella importuna via the Mitochondrial Apoptotic Pathway

2021 ◽  
Vol 2021 ◽  
pp. 1-14
Author(s):  
Chuan Xiong ◽  
Ping Li ◽  
Qiang Luo ◽  
Chia Wei Phan ◽  
Qiang Li ◽  
...  
Keyword(s):  
Hela Cells ◽  
Gel Filtration ◽  
Dependent Manner ◽  
Fruiting Bodies ◽  
Edible Fungi ◽  
Apoptotic Pathway ◽  
Concentration Dependent Manner ◽  
Flow Cytometric ◽  
Medicinal Value ◽  
Morchella Importuna

Morels (Morchella spp.) are a genus of edible fungi with important economic and medicinal value. In this study, a novel peptide (MIPP) was extracted from the fruiting bodies of Morchella importuna using gel filtration chromatography. Structural analysis showed that the molecular mass of MIPP is 831 Da, and it has a simple amino acid sequence: Ser-Leu-Ser-Leu-Ser-Val-Ala-Arg. To explore the antitumor activity of MIPP, the effect of MIPP on HeLa cell apoptosis and the underlying preventative mechanisms were investigated. Results showed that MIPP reduced the viability of HeLa cells in a concentration-dependent manner. TUNEL analysis and flow cytometric examination showed that MIPP decreased cell proliferation via a mitochondrial-dependent pathway, as manifested by downregulation of Bcl-2/Bax, promotion of the movement of cytochrome C from the mitochondria to the cytoplasm, and triggering of caspase-9 and caspase-3. Therefore, MIPP may be a promising tumor-preventive agent, especially in human cervical cancer.

Structural characterization of a water-soluble β-d-glucan from fruiting bodies of Agaricus blazei Murr

2002 ◽  
Vol 337 (15) ◽  
pp. 1417-1421 ◽  
Author(s):  
Qun Dong ◽  
Jian Yao ◽  
Xiao-tong Yang ◽  
Ji-nian Fang
Keyword(s):  
Structural Characterization ◽  
Water Soluble ◽  
Agaricus Blazei ◽  
Fruiting Bodies
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