The mechanical design of computerized glove machine was traditional. It was not only lack of theoretical analysis of key institutions, but running stability needed to be improved. We analyzed the impact of the needle and cams which was based on the computerized glove machine’s knitting theory and key process points. On the basis of SolidWorks, 3-D model of computerized glove machine’s knitting element was created; We imported the 3-D model to ANSYS/LS-DYNA system and realized the motion simulation of needle and cams. As a result, we got the curves of needle’s displacement, velocity and acceleration. According to the simulation parameters of needle’s movement, the knitting element was optimized design. The result reveals that acceleration reaches a maximum of 0.63×105m/s2 when knitting time is 0.052ms. It reduces nearly 16% compare to the result before design optimization of knitting element. The smooth of computerized glove machine is being improved significantly.