Trial of Assessing the Effectiveness of Topical Epigallocatechin-3-Gallate as an Interventional Agent for Radiation-Induced Acute Skin Toxicity to the Breast in Women Undergoing Adjuvant Radiation Therapy

Author(s):  
W. Zhu ◽  
H. Zhao ◽  
L. Jia ◽  
X. Sun ◽  
G. Chen ◽  
...  
1992 ◽  
Vol 78 (6) ◽  
pp. 388-391 ◽  
Author(s):  
Alessandro Testolin ◽  
Franco Pozza ◽  
Sandro Dal Fior ◽  
Gian Paolo Bolzicco ◽  
Gino Antonio Panizzoni ◽  
...  

Primary soft tissue sarcoma of the retroperitoneum is a rare disease. A series of 11 evaluable adult patients with retroperitoneal soft tissue sarcomas is reported. These patients were treated with complete surgery and adjuvant radiation therapy (total dose from 50 to 64 Gy) using an 18 MeV linear accelerator. After a median follow-up of 48 months (range, 6-84), 4 patients had a local-regional recurrence, 3 had distant metastases, and 4 died of progressive disease. Four-year estimated disease-free survival was 54.5% and overall survival was 70%. Treatment was well tolerated by most patients: 7 patients experienced moderate gastrointestinal toxicity, mainly nausea and diarrhea, during radiotherapy; 2 cases had weight loss > 15% at the end of the therapy; and chronic ileitis was observed in 2 cases. We conclude that adjuvant radiotherapy seems to reduce the incidence of local-regional recurrences in these patients. No radiation-induced irreversible injury was observed, but one young woman had amenorrhea after radiotherapy. Controlled clinical trials are warrented to define the role and effiectiveness of adjuvant radiotherapy and/or chemotherapy in retroperitoneal soft tissue sarcomas.


2004 ◽  
Vol 171 (4S) ◽  
pp. 279-280
Author(s):  
Jonathan Rubenstein ◽  
Misop Han ◽  
Sheila A. Hawkins ◽  
William J. Catalona

2004 ◽  
Vol 130 (6) ◽  
pp. 327-333 ◽  
Author(s):  
Hans Geinitz ◽  
Frank B. Zimmermann ◽  
Reinhard Thamm ◽  
Monika Keller ◽  
Raymonde Busch ◽  
...  

2002 ◽  
Vol 74 (4) ◽  
pp. 1033-1037 ◽  
Author(s):  
Abeel A Mangi ◽  
Cameron D Wright ◽  
James S Allan ◽  
John C Wain ◽  
Dean M Donahue ◽  
...  

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