Many industries prefer worldwide business operations due to the economic advantage of globalization on product design and development. These industries increasingly operate globalized multi-tier supply chains and deliver products and services all over the world. This global approach produces huge amounts of heterogeneous data residing at various business operations, and the integration of these data plays an important role. Integrating data from multiple heterogeneous sources need to deal with different data models, database schema, and query languages. This chapter presents a semantic web technology-based data integration framework that uses relational databases and XML data with the help of ontology. To model different source schemas, this chapter proposes a method based on the resource description framework (RDF) graph patterns and query rewriting techniques. The semantic translation between the source schema and RDF ontology is described using query and transformational language SPARQL.