Could oral spleen tyrosine kinase inhibitors lead to neoplastic transformation?

2007 ◽  
Vol 119 (5) ◽  
pp. 1277 ◽  
Author(s):  
Sujoy Khan ◽  
Philip C. Doré ◽  
W.A.C. Sewell
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitors ◽  
Kinase Inhibitors ◽  
Neoplastic Transformation ◽  
Spleen Tyrosine Kinase

Structure-based Drugs Design Studies on Spleen Tyrosine Kinase Inhibitors

2016 ◽  
Vol 13 (9) ◽  
pp. 845-858
Author(s):  
Letícia Cristina Assis ◽  
Letícia Santos Garcia ◽  
Daiana Teixeira Mancini ◽  
Tamiris Maria Assis ◽  
Daniela Rodrigues Silva ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitors ◽  
Kinase Inhibitors ◽  
Spleen Tyrosine Kinase ◽  
Design Studies

Using Ovality to Predict Nonmutagenic, Orally Efficacious Pyridazine Amides as Cell Specific Spleen Tyrosine Kinase Inhibitors

2014 ◽  
Vol 57 (6) ◽  
pp. 2683-2691 ◽  
Author(s):  
Matthew C. Lucas ◽  
Niala Bhagirath ◽  
Eric Chiao ◽  
David M. Goldstein ◽  
Johannes C. Hermann ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitors ◽  
Kinase Inhibitors ◽  
Spleen Tyrosine Kinase

Pyrrolopyrazines as Selective Spleen Tyrosine Kinase Inhibitors

2013 ◽  
Vol 56 (4) ◽  
pp. 1677-1692 ◽  
Author(s):  
Fernando Padilla ◽  
Niala Bhagirath ◽  
Shaoqing Chen ◽  
Eric Chiao ◽  
David M. Goldstein ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitors ◽  
Kinase Inhibitors ◽  
Spleen Tyrosine Kinase

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2012 ◽  
Vol 55 (23) ◽  
pp. 10414-10423 ◽  
Author(s):  
Matthew C. Lucas ◽  
David M. Goldstein ◽  
Johannes C. Hermann ◽  
Andreas Kuglstatter ◽  
Wenjian Liu ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitors ◽  
Rational Design ◽  
Kinase Inhibitors ◽  
Spleen Tyrosine Kinase
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