Molecular profiles of IgE to Phleum pratense in children with grass pollen allergy: Implications for specific immunotherapy

2012 ◽  
Vol 129 (3) ◽  
pp. 834-839.e8 ◽  
Author(s):  
Salvatore Tripodi ◽  
Tullio Frediani ◽  
Sandra Lucarelli ◽  
Francesco Macrì ◽  
Giuseppe Pingitore ◽  
...  
Keyword(s):  
Grass Pollen ◽  
Specific Immunotherapy ◽  
Pollen Allergy ◽  
Phleum Pratense ◽  
Grass Pollen Allergy ◽  
Molecular Profiles

scholarly journals Specific immunotherapy in grass pollen allergy

2012 ◽  
Vol 8 (10) ◽  
pp. 1544-1547 ◽  
Author(s):  
Claire Mailhol ◽  
Alain Didier
Keyword(s):  
Grass Pollen ◽  
Specific Immunotherapy ◽  
Pollen Allergy ◽  
Grass Pollen Allergy

scholarly journals The importance of cross-reactivity in grass pollen allergy

2014 ◽  
Vol 66 (3) ◽  
pp. 1149-1155 ◽  
Author(s):  
Ivana Aleksic ◽  
Olga Vuckovic ◽  
Katarina Smiljanic ◽  
Marija Gavrovic-Jankulovic ◽  
Vera Krsmanovic ◽  
...  
Keyword(s):  
Grass Pollen ◽  
Pollen Allergy ◽  
Immunoblot Analysis ◽  
Cross Reactivity ◽  
Phleum Pratense ◽  
Pollen Extract ◽  
Grass Pollen Allergy ◽  
Number Of Patients

According to the data obtained from in vivo and in vitro testing in Serbia, a significant number of patients have allergic symptoms caused by grass pollen. We examined the protein composition of grass pollens (Dactylis glomerata, Lolium perenne and Phleum pratense) and cross-reactivity in patients allergic to grass pollen from our region. The grass pollen allergen extract was characterized by SDS-PAGE, while cross-reactivity of single grass pollens was revealed by immunoblot analysis. A high degree of cross-reactivity was demonstrated for all three single pollens in the sera of allergic patients compared to the grass pollen extract mixture. Confirmation of the existence of cross-reactivity between different antigenic sources facilitates the use of monovalent vaccines, which are easier to standardize and at the same time prevent further sensitization of patients and reduces adverse reactions.

Trends In Prescribing Of Specific Immunotherapy For Grass Pollen Allergy In Germany: 2005-2012

2014 ◽  
Vol 133 (2) ◽  
pp. AB219
Author(s):  
Ulrich Wahn ◽  
Amanda McDonnell ◽  
Catrina Richards ◽  
Felicia C. Allen-Ramey ◽  
Jakob N. Andreasen ◽  
...  
Keyword(s):  
Grass Pollen ◽  
Specific Immunotherapy ◽  
Pollen Allergy ◽  
Grass Pollen Allergy

Rationale for Specific Immunotherapy of Grass Pollen Allergy with Extracts of Rye Pollen.

Allergy ◽  
1984 ◽  
Vol 39 (6) ◽  
pp. 421-432 ◽  
Author(s):  
H. Løwenstein ◽  
J.-Å. Wihl ◽  
K. Bache Billesbølle ◽  
H. Bøwadt
Keyword(s):  
Grass Pollen ◽  
Specific Immunotherapy ◽  
Pollen Allergy ◽  
Grass Pollen Allergy

scholarly journals Current strategies of allergen-specific immunotherapy

2015 ◽  
Vol 12 (4) ◽  
pp. 16-26
Author(s):  
K S Pavlova ◽  
O M Kurbacheva
Keyword(s):  
Grass Pollen ◽  
Specific Immunotherapy ◽  
Pollen Allergy ◽  
Pollen Extract ◽  
Efficacy And Safety ◽  
Grass Pollen Allergy ◽  
Allergen Specific Immunotherapy ◽  
Natural Exposure ◽  
Safety Studies ◽  
Exposure Conditions

The article discusses the principles of the optimal allergovaccine choice for allergen-specific immunotherapy (ASIT) for grass-pollen-allergy patients; reviewed efficacy and safety studies of the standardized mixt five-grass-pollen extract. Relatively grass sensitization is preferred use mixt grass-pollen extract is thus more suitable for specific immunotherapy, as it contains a broader repertoire of the epitopes, which approximate to the natural exposure conditions.

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