P2-311: In vitro characterization of s44858: A positive allosteric modulator of ampa receptors and GluN2B selective non-competitive nmda receptors antagonist

2015 ◽  
Vol 11 (7S_Part_13) ◽  
pp. P612-P613
Author(s):  
Laurence Danober ◽  
Jean-Yves Thomas ◽  
Sylvie Challal ◽  
Nathalie Rogez ◽  
Karine Albinet ◽  
...  
Keyword(s):  
Nmda Receptors ◽  
Ampa Receptors ◽  
Allosteric Modulator ◽  
Positive Allosteric Modulator ◽  
In Vitro Characterization

P1-077: IN-VITRO CHARACTERIZATION OF SUVN-I2004: A NOVEL MUSCARINIC M1 POSITIVE ALLOSTERIC MODULATOR

2006 ◽  
Vol 14 (7S_Part_5) ◽  
pp. P300-P301
Author(s):  
Ramkumar Subramanian ◽  
Venkat Reddy Mekala ◽  
Maheswari Srirangavaram ◽  
Praveena Nissankararao Mary ◽  
Surekha Edula ◽  
...  
Keyword(s):  
Allosteric Modulator ◽  
Positive Allosteric Modulator ◽  
In Vitro Characterization

[P2-051]: IN VITRO CHARACTERIZATION OF TAK-071: A NOVEL MUSCARINIC M1 RECEPTOR-POSITIVE ALLOSTERIC MODULATOR WITH LOW COOPERATIVITY

2017 ◽  
Vol 13 (7S_Part_12) ◽  
pp. P624-P624 ◽  
Author(s):  
Haruhide Kimura ◽  
Yuji Shimizu ◽  
Atsushi Suzuki ◽  
Emi Kurimoto ◽  
Takao Mandai ◽  
...  
Keyword(s):  
Allosteric Modulator ◽  
Positive Allosteric Modulator ◽  
In Vitro Characterization ◽  
M1 Receptor

In vitro and in vivo characterization of PheTQS, a novel α7 nAChR positive allosteric modulator

2009 ◽  
Vol 78 (7) ◽  
pp. 913 ◽  
Author(s):  
James N.C. Kew ◽  
Selina Mok ◽  
Annette Weil ◽  
Caterina Virginio ◽  
Laura Castelletti ◽  
...  
Keyword(s):  
Allosteric Modulator ◽  
Positive Allosteric Modulator ◽  
Α7 Nachr ◽  
In Vivo Characterization

In vitro and in vivo pharmacological characterization of SSD114, a novel GABAB positive allosteric modulator

2016 ◽  
Vol 791 ◽  
pp. 115-123 ◽  
Author(s):  
Alessandra Porcu ◽  
Carla Lobina ◽  
Daniela Giunta ◽  
Maurizio Solinas ◽  
Claudia Mugnaini ◽  
...  
Keyword(s):  
Allosteric Modulator ◽  
Positive Allosteric Modulator ◽  
Pharmacological Characterization

In vitro and in vivo characterization of the novel GABAB receptor positive allosteric modulator, 2-{1-[2-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-2-piperidinyl}ethanol (CMPPE)

2011 ◽  
Vol 61 (5-6) ◽  
pp. 957-966 ◽  
Author(s):  
Elisabetta Perdona’ ◽  
Vivian J.A. Costantini ◽  
Michela Tessari ◽  
Prisca Martinelli ◽  
Corrado Carignani ◽  
...  
Keyword(s):  
Gabab Receptor ◽  
Allosteric Modulator ◽  
The Novel ◽  
Positive Allosteric Modulator ◽  
In Vivo Characterization

New Positive Allosteric Modulator of AMPA Receptors: in vitro and in vivo Studies

2019 ◽  
Vol 488 (1) ◽  
pp. 304-306
Author(s):  
V. V. Grigoriev ◽  
M. I. Lavrov ◽  
V. L. Zamoyski ◽  
T. L. Garibova ◽  
V. A. Palyulin ◽  
...  
Keyword(s):  
Ampa Receptors ◽  
In Vivo Studies ◽  
Allosteric Modulator ◽  
Positive Allosteric Modulator

In vitro pharmacological characterization of ABT-779, a novel positive allosteric modulator of α7 nAChRs

2011 ◽  
Vol 82 (8) ◽  
pp. 1030 ◽  
Author(s):  
John Malysz ◽  
Jens Halvard Gronlien ◽  
Clark A. Briggs ◽  
David J. Anderson ◽  
Rachid El-Kouhen ◽  
...  
Keyword(s):  
Allosteric Modulator ◽  
Positive Allosteric Modulator ◽  
Pharmacological Characterization ◽  
Α7 Nachrs
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