P4-007: A Novel GabaA A5 Negative Allosteric Modulator Enhances Long-Term Potentiation and Improves Cognition in Preclinical Models

2016 ◽  
Vol 12 ◽  
pp. P1016-P1017
Author(s):  
Miki Nakanishi ◽  
Soichi Kawaharada ◽  
Nobuto Nakanishi ◽  
Keisuke Hazama ◽  
Masato Higashino ◽  
...  
Keyword(s):  
Long Term Potentiation ◽  
Allosteric Modulator ◽  
Preclinical Models ◽  
Term Potentiation ◽  
Negative Allosteric Modulator

[P4-036]: THE NOVEL AMPA RECEPTOR POSITIVE ALLOSTERIC MODULATOR S 47445 RESCUES IN VIVO CA3-CA1 LONG-TERM POTENTIATION AND STRUCTURAL SYNAPTIC CHANGES IN MIDDLE-AGED MICE

2017 ◽  
Vol 13 (7S_Part_26) ◽  
pp. P1270-P1270
Author(s):  
Sylvie Bretin ◽  
Albert Giralt ◽  
María Ángeles Gómez-Climent ◽  
Rafael Alcalá ◽  
Jose Maria Delgado-Garcia ◽  
...  
Keyword(s):  
Ampa Receptor ◽  
Long Term Potentiation ◽  
Allosteric Modulator ◽  
The Novel ◽  
Positive Allosteric Modulator ◽  
Aged Mice ◽  
Term Potentiation ◽  
Synaptic Changes

scholarly journals The AMPA receptor positive allosteric modulator S 47445 rescues in vivo CA3-CA1 long-term potentiation and structural synaptic changes in old mice

2017 ◽  
Vol 123 ◽  
pp. 395-409 ◽  
Author(s):  
Albert Giralt ◽  
María Ángeles Gómez-Climent ◽  
Rafael Alcalá ◽  
Sylvie Bretin ◽  
Daniel Bertrand ◽  
...  
Keyword(s):  
Ampa Receptor ◽  
Long Term Potentiation ◽  
Allosteric Modulator ◽  
Positive Allosteric Modulator ◽  
Term Potentiation ◽  
Synaptic Changes ◽  
Old Mice
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