Type 2 autoimmune hepatitis murine model: The influence of genetic background in disease development

2006 ◽  
Vol 26 (2) ◽  
pp. 82-89 ◽  
Author(s):  
Pascal Lapierre ◽  
Kathie Béland ◽  
Idriss Djilali-Saiah ◽  
Fernando Alvarez
Keyword(s):  
Autoimmune Hepatitis ◽  
Murine Model ◽  
Genetic Background ◽  
Disease Development

scholarly journals Development of a new murine model of type 2 autoimmune hepatitis using a human liver protein

2021 ◽  
Author(s):  
Pablo Thomas-Dupont ◽  
Peter Grube-Pagola ◽  
Irma Yadira Izaguirre-Hernández ◽  
Karina Guadalupe Hernández-Flores ◽  
Elvis Efraín Sánchez-Marce ◽  
...  
Keyword(s):  
Autoimmune Hepatitis ◽  
Murine Model ◽  
Human Liver ◽  
Liver Protein

scholarly journals A murine model of type 2 autoimmune hepatitis: Xenoimmunization with human antigens

Hepatology ◽  
2004 ◽  
Vol 39 (4) ◽  
pp. 1066-1074 ◽  
Author(s):  
Pascal Lapierre ◽  
Idriss Djilali-Saiah ◽  
Susana Vitozzi ◽  
Fernando Alvarez
Keyword(s):  
Autoimmune Hepatitis ◽  
Murine Model

A form of Autoimmune Diabetes in Adults Named LADA – An Update on Essential Features and Controversies

2019 ◽  
Vol 15 (3) ◽  
pp. 172-173 ◽  
Author(s):  
Valdemar Grill ◽  
Bjørn O. Åsvold
Keyword(s):  
Genetic Background ◽  
Clinical Utility ◽  
Autoimmune Diabetes ◽  
Classical Type ◽  
Phenotypic Characteristics ◽  
Latent Autoimmune Diabetes ◽  
The Impact

Latent Autoimmune Diabetes in the Adult, LADA has been investigated less than “classical” type 1 and type 2 diabetes and the criteria for and the relevance of a LADA diagnosis has been challenged. Despite the absence of a genetic background that is exclusive to LADA, this form of diabetes displays phenotypic characteristics that distinguish it from other forms of diabetes. LADA is heterogeneous in terms of the impact of autoimmunity and lifestyle factors, something that poses problems as to therapy and follow-up perhaps particularly in those with marginal positivity. Yet, there appears to be clear clinical utility in classifying individuals as LADA.

scholarly journals Development of a diet-induced murine model of diabetes featuring cardinal metabolic and pathophysiological abnormalities of type 2 diabetes

Biology Open ◽  
2016 ◽  
Vol 5 (8) ◽  
pp. 1149-1162 ◽  
Author(s):  
Jodie L. Morris ◽  
Tahnee L. Bridson ◽  
Md Abdul Alim ◽  
Catherine M. Rush ◽  
Donna M. Rudd ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Murine Model

Attenuating the Inflammatory Changes of Type 2 Diabetes with Whole Body Vibration in a Murine Model

2013 ◽  
Vol 179 (2) ◽  
pp. 190
Author(s):  
M. Masoumy ◽  
J.C. Yu ◽  
K.H. Wenger ◽  
J.Y. Liu ◽  
S.T. Hsieh ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Murine Model ◽  
Whole Body Vibration ◽  
Whole Body ◽  
Body Vibration ◽  
Inflammatory Changes

Analysis of hepatitis C virus genome in patients with autoimmune hepatitis type 2

1994 ◽  
Vol 106 (6) ◽  
pp. 1603-1610 ◽  
Author(s):  
Kojiro Michitaka ◽  
Marilena Durazzo ◽  
Hans L. Tillmann ◽  
Diana Walker ◽  
Thomas Philipp ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Autoimmune Hepatitis ◽  
Virus Genome

scholarly journals A murine model of neurofibromatosis type 2 that accurately phenocopies human schwannoma formation

2014 ◽  
Vol 24 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Jeffrey R. Gehlhausen ◽  
Su-Jung Park ◽  
Ann E. Hickox ◽  
Matthew Shew ◽  
Karl Staser ◽  
...  
Keyword(s):  
Murine Model ◽  
Neurofibromatosis Type ◽  
Neurofibromatosis Type 2

scholarly journals Autoimmune Hepatitis with Anti Centromere Antibodies

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Moushumi Lodh ◽  
Debkant Pradhan ◽  
Ashok Parida
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Autoimmune Hepatitis ◽  
Diabetes Mellitus Patient ◽  
Accurate Diagnosis ◽  
Anticentromere Antibody ◽  
Anticentromere Antibodies ◽  
Laboratory Investigations ◽  
Optimum Management

We present the case report of a 49-year-old type 2 diabetes mellitus patient presenting with abdominal pain and black stool for 15 days. A proper workup of laboratory investigations helped us diagnose autoimmune hepatitis with anticentromere antibodies. The authors would like to highlight that screening AIH patients for anticentromere antibody is not mandatory but can be considered, especially in the presence of disease-related symptomatology for quicker, more accurate diagnosis and optimum management.

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