scholarly journals Insights into the knowledge of complex diseases: Environmental infectious/toxic agents as potential etiopathogenetic factors of systemic sclerosis

2021 ◽  
Vol 124 ◽  
pp. 102727
Author(s):  
Clodoveo Ferri ◽  
Maria-Cristina Arcangeletti ◽  
Elisabetta Caselli ◽  
Krystyna Zakrzewska ◽  
Clara Maccari ◽  
...  
Author(s):  
F. G. Zaki

Fetal and neonatal liver injury induced by agents circulating in maternal plasma, even though well recognized, its morphological manifestations are not yet established. As part of our studies of fetal and neonatal liver injury induced by maternal nutritional disorders, metabolic impairment and toxic agents, the effects of two anti-inflammatory steroids have been recently inves tigated.Triamcinolone and methyl prednisolone were injected each in a group of rats during pregnancy at a-dosage level of 2 mgm three times a week. Fetal liver was studied at 18 days of gestation. Litter size and weight markedly decreased than those of control rats. Stillbirths and resorption were of higher incidence in the triamcinolone group than in those given the prednisolone.


2008 ◽  
Vol 41 (18) ◽  
pp. 21
Author(s):  
SHARON WORCESTER
Keyword(s):  

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