Development and validation of a sensitive gas chromatography–ammonia chemical ionization mass spectrometry method for the determination of tabun enantiomers in hemolysed blood and plasma of different species

2010 ◽  
Vol 878 (17-18) ◽  
pp. 1290-1296 ◽  
Author(s):  
Oliver Tenberken ◽  
Franz Worek ◽  
Horst Thiermann ◽  
Georg Reiter
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Chemical Ionization ◽  
Ionization Mass Spectrometry ◽  
Chemical Ionization Mass Spectrometry ◽  
Ionization Mass ◽  
Spectrometry Method ◽  
Mass Spectrometry Method ◽  
Development And Validation

Determination of Desaminosulfamethazine, Sulfamethazine, and N4-Acetylsulfamethazine by Gas Chromatography with Electron Capture Detection and Confirmation by Gas Chromatography-Chemical Ionization Mass Spectrometry

1987 ◽  
Vol 70 (3) ◽  
pp. 546-553
Author(s):  
Jean E Matusik ◽  
Greg C Guyer ◽  
Jaroslav N Geleta ◽  
Charlie J Barnes
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Electron Capture ◽  
Chemical Ionization ◽  
Ionization Mass Spectrometry ◽  
Chemical Ionization Mass Spectrometry ◽  
Electron Capture Detection ◽  
Ionization Mass ◽  
Veal Calf

Abstract An electron capture gas chromatographic method for the determination of sulfamethazine was modified to separate and quantitate simultaneously sulfamethazine and 2 of its metabolites, N4-acetylsulfamethazine and desaminosulfamethazine. The modified method was applied to incurred residues in a veal calf depletion study and to incurred residues in swine tissues. With capillary column gas chromatography-positive ion chemical ionization mass spectrometry, confirmation of the identities of incurred desaminosulfamethazine, N4-acetylsulfamethazine, and sulfamethazine in tissues was obtained from a single injection.

Multipesticide Determination in Surface Water by Gas Chromatography/Chemical Ionization/Mass Spectrometry/Ion Trap Detection

1991 ◽  
Vol 74 (6) ◽  
pp. 982-986
Author(s):  
Gregory C Mattern ◽  
Judith B Louis ◽  
Joseph D Rosen
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Surface Water ◽  
Chemical Ionization ◽  
Ion Trap ◽  
Ionization Mass Spectrometry ◽  
Chemical Ionization Mass Spectrometry ◽  
Ionization Mass ◽  
Average Coefficient

Abstract An improved method for the determination of trace levels of pesticides in surface water has been developed and was used to analyze 20 target pesticides in New Jersey. Pesticides were extracted from 2 L water samples, using a mixture of XAD-2 and XAD-7 resins, and were determined by gas chromatography/chemical ionization mass spectrometry with ion trap detection. Average recoveries (performed in triplicate at the 1 ppb level, except for captan and chlorothalonil at 5 ppb) were between 75 and 113%, with an average coefficient of variation of 9%. Most of the pesticides (alachlor, atrazine, butylate, carbofuran, chlorpyrifos, diazinon, fonofos, isofenphos, metolachlor, metribuzin, parathion, and simazine) had limits of detection (LODs) of 0.005 ppb or lower, while some (carbaryl, cyanazine, fenamiphos, linuron, pendlmethalin, and terbufos) had LODs between 0.005 and 0.05 ppb. Captan and chlorothalonil had LODs of 1 ppb. Of 31 samples analyzed, 29 contained one or more of the following pesticides: alachlor, atrazine, carbaryl, chlorpyrifos, cyanazine, diazinon, isofenphos, linuron, metolachlor, and simazine in concentrations between trace (<0.025 ppb) and 5.48 ppb.

Sign in / Sign up

Export Citation Format

Share Document