Purification of antibody fragments for the reduction of charge variants using cation exchange chromatography

Journal of Chromatography B ◽

10.1016/j.jchromb.2018.01.030 ◽

2018 ◽

Vol 1080 ◽

pp. 20-26 ◽

Author(s):

Hong Jai Lee ◽

Chung Min Lee ◽

Kyunghwa Kim ◽

Jung Min Yoo ◽

Sung-muk Kang ◽

...

Keyword(s):

Cation Exchange ◽

Exchange Chromatography ◽

Antibody Fragments ◽

Cation Exchange Chromatography ◽

Charge Variants

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Separation of monoclonal antibody charge variants using cation exchange chromatography: Resins and separation conditions optimization

Separation and Purification Technology ◽

10.1016/j.seppur.2019.116136 ◽

2020 ◽

Vol 235 ◽

pp. 116136 ◽

Author(s):

Shu-Ying Jing ◽

Jin-Xia Gou ◽

Dong Gao ◽

Hai-Bin Wang ◽

Shan-Jing Yao ◽

...

Keyword(s):

Monoclonal Antibody ◽

Cation Exchange ◽

Exchange Chromatography ◽

Cation Exchange Chromatography ◽

Charge Variants ◽

Separation Conditions

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Method development for the separation of monoclonal antibody charge variants in cation exchange chromatography, Part I: Salt gradient approach

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2014.08.035 ◽

2015 ◽

Vol 102 ◽

pp. 33-44 ◽

Author(s):

Szabolcs Fekete ◽

Alain Beck ◽

Jenő Fekete ◽

Davy Guillarme

Keyword(s):

Monoclonal Antibody ◽

Cation Exchange ◽

Method Development ◽

Exchange Chromatography ◽

Cation Exchange Chromatography ◽

Salt Gradient ◽

Charge Variants ◽

Gradient Approach

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Method development for the separation of monoclonal antibody charge variants in cation exchange chromatography, Part II: pH gradient approach

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2014.09.032 ◽

2015 ◽

Vol 102 ◽

pp. 282-289 ◽

Author(s):

Szabolcs Fekete ◽

Alain Beck ◽

Jenő Fekete ◽

Davy Guillarme

Keyword(s):

Monoclonal Antibody ◽

Cation Exchange ◽

Method Development ◽

Exchange Chromatography ◽

Ph Gradient ◽

Cation Exchange Chromatography ◽

Charge Variants ◽

Gradient Approach

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Double-peak elution profile of a monoclonal antibody in cation exchange chromatography is caused by histidine-protonation-based charge variants

Journal of Chromatography A ◽

10.1016/j.chroma.2015.11.008 ◽

2015 ◽

Vol 1424 ◽

pp. 92-101 ◽

Author(s):

Haibin Luo ◽

Mingyan Cao ◽

Kelcy Newell ◽

Christopher Afdahl ◽

Jihong Wang ◽

...

Keyword(s):

Monoclonal Antibody ◽

Cation Exchange ◽

Exchange Chromatography ◽

Elution Profile ◽

Cation Exchange Chromatography ◽

Double Peak ◽

Charge Variants

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Effects of carboxypeptidase B treatment and elevated temperature on recombinant monoclonal antibody charge variants in cation-exchange chromatography analysis

Archives of Pharmacal Research ◽

10.1007/s12272-016-0818-5 ◽

2016 ◽

Vol 39 (10) ◽

pp. 1472-1481 ◽

Author(s):

Do Gyun Kim ◽

Hyoung Jin Kim ◽

Hong-Jin Kim

Keyword(s):

Monoclonal Antibody ◽

Elevated Temperature ◽

Cation Exchange ◽

Exchange Chromatography ◽

Cation Exchange Chromatography ◽

Carboxypeptidase B ◽

Chromatography Analysis ◽

Recombinant Monoclonal Antibody ◽

Charge Variants

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Multiattribute Monitoring of Antibody Charge Variants by Cation-Exchange Chromatography Coupled to Native Mass Spectrometry

Journal of the American Society for Mass Spectrometry ◽

10.1021/jasms.0c00446 ◽

2021 ◽

Author(s):

Markus Haberger ◽

Anna-Katharina Heidenreich ◽

Michaela Hook ◽

Jürgen Fichtl ◽

Rainer Lang ◽

...

Keyword(s):

Mass Spectrometry ◽

Cation Exchange ◽

Native Mass Spectrometry ◽

Exchange Chromatography ◽

Cation Exchange Chromatography ◽

Charge Variants

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Enrichment of uranium isotopes by cation-exchange chromatography of uranium(IV)—malic acid and —lactic acid complexes

Journal of Chromatography A ◽

10.1016/s0021-9673(00)87279-9 ◽

1982 ◽

Vol 248 (2) ◽

pp. 281-288 ◽

Author(s):

Takao Oi ◽

Yoichi Sakuma ◽

Makoto Okamoto ◽

Masunobu Maeda

Keyword(s):

Lactic Acid ◽

Cation Exchange ◽

Exchange Chromatography ◽

Uranium Isotopes ◽

Cation Exchange Chromatography

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Strong cation-exchange chromatography of proteins on a sulfoalkylated monolithic cryogel

Journal of Chromatography A ◽

10.1016/j.chroma.2015.01.075 ◽

2015 ◽

Vol 1386 ◽

pp. 13-21 ◽

Author(s):

Işık Perçin ◽

Rushd Khalaf ◽

Bastian Brand ◽

Massimo Morbidelli ◽

Orhan Gezici

Keyword(s):

Cation Exchange ◽

Exchange Chromatography ◽

Cation Exchange Chromatography ◽

Strong Cation Exchange ◽

Strong Cation Exchange Chromatography

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Decision letter for "Straightforward method for calibration of mechanistic cation exchange chromatography models for industrial applications"

10.1002/btpr.2984/v1/decision1 ◽

2020 ◽

Keyword(s):

Cation Exchange ◽

Industrial Applications ◽

Exchange Chromatography ◽

Cation Exchange Chromatography ◽

Straightforward Method

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Concentration of Recombinant Baculovirus by Cation-Exchange Chromatography

BioTechniques ◽

10.2144/99265bm07 ◽

1999 ◽

Vol 26 (5) ◽

pp. 834-840 ◽

Author(s):

James Barsoum

Keyword(s):

Cation Exchange ◽

Recombinant Baculovirus ◽

Exchange Chromatography ◽

Cation Exchange Chromatography

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