In vitro reconstruction of epidermis from primary Darier's disease keratinocytes replicates the histopathological phenotype

2013 ◽  
Vol 71 (2) ◽  
pp. 138-140 ◽  
Author(s):  
Catherine Lambert de Rouvroit ◽  
Céline Charlier ◽  
Damien Lederer ◽  
Valérie De Glas ◽  
Evelyne De Vuyst ◽  
...  
Keyword(s):  
Darier’S Disease ◽  
Darier's Disease

scholarly journals Treatment of Darier’s disease with oral magnesium: a case report

2018 ◽  
Vol 6 ◽  
pp. 2050313X1879507
Author(s):  
Heidi Oi-Yee Li ◽  
Sophia Colantonio ◽  
Nordau Kanigsberg
Keyword(s):  
Endoplasmic Reticulum ◽  
Magnesium Chloride ◽  
Therapeutic Option ◽  
The Novel ◽  
Darier’S Disease ◽  
Darier Disease ◽  
Darier's Disease ◽  
Effective Therapeutic Option ◽  
Oral Magnesium

Darier’s disease, an autosomal dominant genodermatosis, arises from a mutation in the ATP2A2 gene that codes for sarco/endoplasmic reticulum Ca2+-ATPase in the endoplasmic reticulum and is characterized by greasy keratotic papules commonly found in seborrheic regions. Conventional treatments, including topical corticosteroids, antibiotics, antifungals and retinoids, often have limited efficacy. The present article reports the novel use of oral magnesium chloride supplementation (300 mg daily) in the treatment of Darier disease. After 5 years of limited improvement using conventional therapies, significant improvements in neck lesions were observed within 1 month of starting oral magnesium chloride. This suggests that oral magnesium chloride may be an effective therapeutic option for Darier disease, although further in vitro and clinical trials are necessary to evaluate its clinical efficacy.

Hemorrhagic Darier's disease

1993 ◽  
Vol 129 (4) ◽  
pp. 511-512 ◽  
Author(s):  
P. L. Foresman
Keyword(s):  
Darier’S Disease ◽  
Darier's Disease

Hailey-Hailey Disease with Hyperkeratotic Verrucus Lesions (Similar to Darier's Disease): A Case Report.

1992 ◽  
Vol 54 (6) ◽  
pp. 1074-1078
Author(s):  
Toshiki ITOH ◽  
Youichi INABA ◽  
Takehiko NAKAMURA ◽  
Tomomichi ONO
Keyword(s):  
Case Report ◽  
Darier’S Disease ◽  
Darier's Disease

A Japanese case of segmental Darier's disease caused by mosaicism for the ATP2A2 mutation

2003 ◽  
Vol 149 (1) ◽  
pp. 185-188 ◽  
Author(s):  
T. Wada ◽  
Y. Shirakata ◽  
H. Takahashi ◽  
S. Murakami ◽  
H. Iizuka ◽  
...  
Keyword(s):  
Japanese Case ◽  
Darier’S Disease ◽  
Darier's Disease
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