scholarly journals Reply to: “Underestimation of occult hepatitis C virus infection in chronic haemodialysis and kidney transplant patients”

2014 ◽  
Vol 61 (5) ◽  
pp. 1185-1186 ◽  
Author(s):  
Seema Baid-Agrawal ◽  
Thomas Berg
2020 ◽  
Vol 18 ◽  
Author(s):  
Mohammed Al Atbee ◽  
Saad Shaheen Al-Taher ◽  
Majid Alabbood

Background: Up to date, there is no consensus on the best combination of direct-acting antiviral to treat hepatitis C virus in kidney transplant recipients. Objective: This study aims to analyze the efficacy of combination of sofosbuvir and ledipasvir regimen for treatment of hepatitis C virus infected kidney transplant patients. Method: A cross-sectional study conducted in a nephrology clinic and the Nephrology Center in Basrah Teaching Hospital from June 2015 to June 2018. Ledifos (90 mg Ledipasvir and 400 mg Sofosbuvir fixed-dose) was given as a single daily dose for all the participants for 12 weeks. Response for therapy was tested by follow up hepatitis C virus load at the end of 12 weeks and 24 weeks. The sustained virological response was defined as negative viral load of hepatitis C virus (aviremia) at the end of therapy. This study was done according to the Helsinki Congress. Results: A total of 60 (16 females) patients with renal transplantation and hepatitis C virus infection were included. Mean age was 40±6.2 years. A sustained virological response observed in all of the patients who received Ledifos after 12 and 24 weeks of therapy for all genotypes (1a, 1b and 4); p= 0.0001. Genotype 1a was more prevalent among males, 34 (56.6%); p= 0.0001, and it was the most common genotype tested negative serologically, 11 (18.3%). Conclusion: Ledifos therapy is effective and safe option for the treatment of hepatitis C virus infection in the post–renal transplant setting.


Hepatology ◽  
2018 ◽  
Vol 68 (4) ◽  
pp. 1298-1307 ◽  
Author(s):  
Nancy Reau ◽  
Paul Y. Kwo ◽  
Susan Rhee ◽  
Robert S. Brown ◽  
Kosh Agarwal ◽  
...  

2020 ◽  
Vol 18 (2) ◽  
pp. 206-209 ◽  
Author(s):  
Ramin Yaghobi ◽  
Mohammad Javad Kazemi ◽  
Bita Geramizadeh ◽  
Seyed Ali Malek Hosseini ◽  
Javad Moayedi

1998 ◽  
Vol 66 (4) ◽  
pp. 471-476 ◽  
Author(s):  
Touru Hanafusa ◽  
Yasuji Ichikawa ◽  
Hidefumi Kishikawa ◽  
Masahiro Kyo ◽  
Takanobu Fukunishi ◽  
...  

2009 ◽  
Vol 23 (6) ◽  
pp. 594-601 ◽  
Author(s):  
Florence Nicot ◽  
Nassim Kamar ◽  
Bernard Mariamé ◽  
Lionel Rostaing ◽  
Christophe Pasquier ◽  
...  

1997 ◽  
Vol 29 (1-2) ◽  
pp. 783 ◽  
Author(s):  
J.-L. Garnier ◽  
P. Chevallier ◽  
J.-M. Dubernard ◽  
C. Trepo ◽  
J.-L. Touraine ◽  
...  

Renal Failure ◽  
2008 ◽  
Vol 30 (1) ◽  
pp. 81-87 ◽  
Author(s):  
Visnja Lezaic ◽  
Milan Stosovic ◽  
Jelena Marinkovic ◽  
Vanja Rangelov ◽  
Ljubica Djukanovic

2007 ◽  
Vol 18 (2) ◽  
pp. 97-115 ◽  
Author(s):  
Seema Baid-Agrawal ◽  
Manuel Pascual ◽  
Darius Moradpour ◽  
Ulrich Frei ◽  
Nina Tolkoff-Rubin

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