Experimental perspective for reactive separation of malonic acid using TBP in natural non-toxic solvents

2020 ◽  
Vol 91 ◽  
pp. 273-284
Author(s):  
Vicky R. Dhongde ◽  
Biswajit S. De ◽  
Kailas L. Wasewar ◽  
Priyanka Gupta ◽  
Sushil Kumar
Keyword(s):  
Malonic Acid ◽  
Reactive Separation

3-(s-Hydrindacen-4-yl)propylamines and 4-(s-hydrindacen-4-yl)butylamines; Synthesis and pharmacological screening

1981 ◽  
Vol 46 (8) ◽  
pp. 1800-1807 ◽  
Author(s):  
Zdeněk Vejdělek ◽  
Marie Bartošová ◽  
Miroslav Protiva
Keyword(s):  
Malonic Acid ◽  
Local Anaesthetics ◽  
Lithium Aluminium Hydride ◽  
Spasmolytic Activity ◽  
Lithium Aluminium ◽  
Malonic Acid Derivatives ◽  
Pharmacological Screening ◽  
Hydroxyethyl Piperazine

4-Chloromethyl-s-hydrindacene (VIIa) was transformed via the malonic acid derivatives VIIIa and IXa to the acid Xb which afforded in four steps the homological acid Xc. Reactions of chlorides of both acids (XIbc ) with dimethylamine, 1-methylpiperazine and 1-(2-hydroxyethyl)piperazine led to the amides XIIbc-XIVbc which were reduced with lithium aluminium hydride to the title compounds IVcd-VIcd. The amines obtained show central neuroleptic effects only in subtoxic doses; they are also potent local anaesthetics and have significant spasmolytic activity of the neurotropic as well as musculotropic type.

An NMR relaxation study on the hydrogen dynamics in malonic acid

1987 ◽  
Vol 111 (3) ◽  
pp. 439-443 ◽  
Author(s):  
Stanislz.xlaw Idziak ◽  
Narcyz Piślewski
Keyword(s):  
Malonic Acid ◽  
Nmr Relaxation ◽  
Relaxation Study

scholarly journals Perspectives on Reactive Separation and Removal of Hydrogen Sulfide

2021 ◽  
pp. 100105
Author(s):  
Kalyani Jangam ◽  
Yu-Yen Chen ◽  
Lang Qin ◽  
Liang-Shih Fan
Keyword(s):  
Hydrogen Sulfide ◽  
Reactive Separation

THE IONIZATION CONSTANTS OF p-NITROPHENYLACETIC AND PHENYLMALONIC ACIDS

1933 ◽  
Vol 8 (5) ◽  
pp. 447-449 ◽  
Author(s):  
Steward Basterfield ◽  
James W. Tomecko
Keyword(s):  
Benzoic Acid ◽  
Nitro Group ◽  
Malonic Acid ◽  
Phenylacetic Acid ◽  
Ionization Constants ◽  
Side Chain ◽  
Cooh Group ◽  
Conductivity Data ◽  
Nitrobenzoic Acid ◽  
Phenylmalonic Acid

The ionization constants of p-nitrophenylacetic and phenylmalonic acids have been determined from conductivity data. The value of K for p-nitrophenylacetic acid at 25 °C. is 1.04 × 10−4, about twice that of phenylacetic acid. The nitro group in the nucleus has not as powerful an effect on the ionization when the COOH group is in the side chain as it has when both nitro group and COOH are in the nucleus. K for p-nitrobenzoic acid is six times as great as K for benzoic acid. K for phenylmalonic acid is 2. 77 × 10−3 as compared with 1.6 × 10−3 for malonic acid.

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