Randomized Study Comparing Use of THUNDERBEAT Technology vs Standard Electrosurgery during Laparoscopic Radical Hysterectomy and Pelvic Lymphadenectomy for Gynecologic Cancer

Background and ObjectivesThe aim of this study was to compare the feasibility, morbidity, and recurrence rate of total laparoscopic radical hysterectomy (LRH) with those of abdominal radical hysterectomy (ARH) for bulky early-stage cervical cancer.MethodsWe performed a retrospective cohort study of 112 patients with stage IB1 or IIA2 cervical cancer in which the tumor diameter was 3 cm or greater. All patients underwent LRH (n = 30) or ARH (n = 82) with pelvic lymphadenectomy and/or para-aortic lymph node sampling between May 2011 and November 2014. Perioperative outcomes were compared between the 2 surgical groups.ResultsThe laparoscopic approach consisted of 4 trocar insertions. Age, tumor diameter, and pelvic lymph nodes significantly differed between the 2 cohorts. Body mass index, International Federation of Gynecology and Obstetrics stage, histologic type and grade, deep stromal invasion, lymphovascular space invasion, positive margins, and adjuvant therapy were not significantly different between the 2 cohorts. Laparoscopic radical hysterectomy exhibited favorable results compared with ARH in terms of operating time, blood loss, intestinal exhaust time, and length of hospital stay. In addition, recurrence was observed in 5 LRH patients (16.7%) and 9 ARH patients (11.7%).ConclusionsThe surgical outcomes of LRH with pelvic lymphadenectomy and/or para-aortic lymph node sampling exhibited a similar therapeutic efficacy to those of the ARH approach.

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A prospective randomized study comparing retroperitoneal drainage with no drainage and no peritonization following radical hysterectomy and pelvic lymphadenectomy for invasive cervical cancer

Journal of Obstetrics and Gynaecology Research ◽

10.1046/j.1341-8076.2002.00027.x ◽

2002 ◽

Vol 28 (3) ◽

pp. 149-153 ◽

Cited By ~ 17

Author(s):

Jatupol Srisomboon ◽

Chailert Phongnarisorn ◽

Prapaporn Suprasert ◽

Chalong Cheewakriangkrai ◽

Sitthicha Siriaree ◽

...

Keyword(s):

Cervical Cancer ◽

Radical Hysterectomy ◽

Randomized Study ◽

Invasive Cervical Cancer ◽

Pelvic Lymphadenectomy ◽

Prospective Randomized Study ◽

Retroperitoneal Drainage

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Laparoscopic Radical Hysterectomy and Pelvic Lymphadenectomy Can Be Routinely Used for Treatment of Early-stage Cervical Cancer: A Single-institute Experience With 404 Patients

Journal of Minimally Invasive Gynecology ◽

10.1016/j.jmig.2014.09.009 ◽

2015 ◽

Vol 22 (2) ◽

pp. 199-204 ◽

Cited By ~ 11

Author(s):

Lu Yang ◽

Jing Cai ◽

Weihong Dong ◽

Yi Shen ◽

Zhoufang Xiong ◽

...

Keyword(s):

Cervical Cancer ◽

Radical Hysterectomy ◽

Early Stage ◽

Pelvic Lymphadenectomy ◽

Laparoscopic Radical Hysterectomy ◽

Early Stage Cervical Cancer

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Effectiveness of modified complex decongestive physiotherapy for preventing lower extremity lymphedema after radical surgery for cervical cancer: a randomized controlled trial

International Journal of Gynecological Cancer ◽

10.1136/ijgc-2019-000911 ◽

2020 ◽

Vol 30 (6) ◽

pp. 757-763 ◽

Cited By ~ 1

Author(s):

Xia Wang ◽

Yan Ding ◽

Hui-Yuan Cai ◽

Jing You ◽

Fang-Qin Fan ◽

...

Keyword(s):

Cervical Cancer ◽

Health Education ◽

Lower Extremity ◽

Radical Hysterectomy ◽

Radical Surgery ◽

Intervention Group ◽

Pelvic Lymphadenectomy ◽

Control Group ◽

Laparoscopic Radical Hysterectomy ◽

Complex Decongestive Physiotherapy

BackgroundThere is a lack of evidence in support of any prophylactic measure to prevent secondary lower extremity lymphedema after radical hysterectomy among patients with cervical cancer. This study aimed to determine the effectiveness of modified complex decongestive physiotherapy in reducing the risk of secondary lower extremity lymphedema after radical surgery.MethodsA randomized single-blind clinical trial was conducted in 120 patients with cervical cancer who underwent laparoscopic radical hysterectomy with pelvic lymphadenectomy between January 2016 and April 2017 in the Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China. Participants were randomly assigned to a modified complex decongestive physiotherapy intervention group (n=60) or control group (n=60). The intervention group received a modified complex decongestive physiotherapy program, which included manual lymph drainage, compression hosiery, regular exercise, and health education. The control group only received a health education program. The main outcome was the incidence of secondary lower extremity lymphedema.ResultsA total of 117 patients with cervical cancer completed a 1-year follow-up. Twenty-eight (23.9%) patients developed secondary lower extremity lymphedema (20 (34.5%) patients in the control group and 8 (13.6%) in the intervention group). The incidence of secondary lower extremity lymphedema was significantly higher in the control group than in the intervention group (p=0.008; OR 0.30 (95% CI 0.12 to 0.75). The median percentage of excess volume was significantly less in the intervention group (2.1%, IQR 0.5–3.4%) than in the control group (2.96%, IQR 1.1–4.98%); (p=0.042). The mean (SD) onset time of lymphedema was 8 (2.00) months vs 4.6 (2.82) months in the intervention and control groups, respectively (p=0.004).ConclusionsThis randomized trial showed that modified complex decongestive physiotherapy is effective for preventing lower extremity lymphedema in patients with cervical cancer after laparoscopic radical hysterectomy with pelvic lymphadenectomy.

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