scholarly journals Prevalence and characterization of neonatal skin disorders in the first 72 h of life

2017 ◽  
Vol 93 (3) ◽  
pp. 238-245 ◽  
Author(s):  
Flávia Pereira Reginatto ◽  
Damie DeVilla ◽  
Fernanda M. Muller ◽  
Juliano Peruzzo ◽  
Letícia P. Peres ◽  
...  
Keyword(s):  
Skin Disorders ◽  
Neonatal Skin

scholarly journals Prevalence and characterization of neonatal skin disorders in the first 72 h of life

2017 ◽  
Vol 93 (3) ◽  
pp. 238-245
Author(s):  
Flávia Pereira Reginatto ◽  
Damie DeVilla ◽  
Fernanda M. Muller ◽  
Juliano Peruzzo ◽  
Letícia P. Peres ◽  
...  
Keyword(s):  
Skin Disorders ◽  
Neonatal Skin

Birth marks and neonatal skin disorders. From angel kiss to epidermolysis bullosa

2014 ◽  
Vol 155 (13) ◽  
pp. 500-508 ◽  
Author(s):  
Zsanett Csoma ◽  
Angéla Meszes ◽  
Rita Ábrahám ◽  
Judit Bakki ◽  
Zita Gyurkovits ◽  
...  
Keyword(s):  
Newborn Infants ◽  
Vascular Lesions ◽  
Whole Body ◽  
Special Treatment ◽  
Skin Disorders ◽  
Cutaneous Lesions ◽  
Developmental Abnormalities ◽  
Pigmented Lesions ◽  
Mongolian Spot ◽  
Neonatal Skin

Introduction: At present there are no exact epidemiologic data on the prevalence of neonatal skin disorders and birth marks in Hungary. Aim: The aim of the authors was to investigate the prevalence of skin disorders in mature healthy neonates after birth. Method: The survey was carried out in the Neonatal Care Unit at the Department of Obstetrics and Gynaecology at the University of Szeged between April, 2012 and May, 2013. Results:A total of 2289 newborn infants underwent whole-body screening skin examinations. At least one skin manifestation was found in 63% of the neonates. The major groups of skin disorders were transient benign cutaneous lesions, vascular lesions, pigmented lesions, traumatic, iatrogenic, congenital or acquired disorders with skin injuries, developmental abnormalities and benign skin tumours. The most frequent transient cutaneous lesions were erythema toxicum neonatorum, sebaceous hyperplasia and desquamation. The most common vascular lesions were naevus simplex, haemangioma and haemangioma precursor lesion, while the most frequently observed pigmented lesions were congenital melanocytic naevi and Mongolian spot. Conclusions: In the vast majority of cases, special treatment was not necessary, but 5.27% of the neonates required local dermatologic therapy, and in 9.2% of neonates follow up was recommended. Orv. Hetil., 2014, 155(13), 500–508.

scholarly journals DESIGN OF DERMA STICKS OF ANDROGAPHIS PANICULATA FOR THE TREATMENT OF GYNAECOLOGICAL SKIN DISORDERS

2018 ◽  
Vol 10 (1) ◽  
pp. 8
Author(s):  
Savita Sonawane K. ◽  
Purushotham Rao
Keyword(s):  
Skin Irritation ◽  
Phase Iii ◽  
Vaginal Candidiasis ◽  
Vaginal Mucosa ◽  
Skin Disorders ◽  
Healthy Human ◽  
Phase Ii Studies ◽  
Human Volunteers ◽  
Phase Iii Studies

Objective: Vaginal candidiasis are often painful and uncomfortable and can include intense itching, irritation, vaginal discharge and dysuria. Gynaecological skin disorders referring to inflammatory and infectious conditions affecting the vaginal mucosa and vulvitis often accompanies vagina pain, itching and burning sensation. Herbal therapy is gaining popularity of women on account of it’s reduced side effect and restoration of the normal vaginal flora. Plants reported to possess activity or used in traditional systems of medicine for prevention and treatment of vaginitis. Therefore, it was found essential to find an alternative to counter all the above disadvantages effectively and hence in the present work, formulation and development of medicated sticks has been planned with the herbal drug Androgaphis Paniculata which is very well known for the anti bacterial and anti fungal activity.Methods: The preparation and characterization of medicated sticks was carried out in four phases. Phase I studies includes preparation of medicated derma sticks using the ointment bases with varied concentrations of waxes. Phase II studies involves characterization of prepared medicated derma sticks like weight, thickness and length. Phase III studies involves stability studies of prepared formulations. Phase IV Studies involves anti microbial studies by zone inhibition method. .Phase V: Primary skin irritation studies carried out on rabbits and guinea pigs and in healthy human volunteers showed no sensitization and edema on skin after 72 h of application.Results: The results of present study revealed that the prepared medicated sticks of Androgaphis Paniculata are convenient, equally effective, without any contamination chances on application and free from skin irritation.Conclusion:The present work is a unique piece of contribution to the drug industry. The results will be useful to industry RandD for further investigations. The continuation of these work clinical studies is in progress.Objective: Vaginal candidiasis are often painful and uncomfortable and can include intense itching, irritation, vaginal discharge and dysuria. Gynaecological skin disorders referring to inflammatory and infectious conditions affecting the vaginal mucosa and vulvitis often accompanies vagina pain, itching and burning sensation. Herbal therapy is gaining popularity of women on account of its reduced side effect and restoration of the normal vaginal flora. Plants reported to possess activity or used in traditional systems of medicine for prevention and treatment of vaginitis. Therefore, it was found essential to find an alternative to counter all the above disadvantages effectively and hence in the present work, formulation and development of medicated sticks have been planned with the herbal drug Androgaphis Paniculata which is very well known for the antibacterial and antifungal activity.Methods: The preparation and characterization of medicated sticks were carried out in four phases. Phase I studies include preparation of medicated derma sticks using the ointment bases with varied concentrations of waxes. Phase II studies involve characterization of prepared medicated derma sticks like weight, thickness and length. Phase III studies involves stability studies of prepared formulations. Phase IV Studies involves antimicrobial studies by zone inhibition method. .Phase V: Primary skin irritation studies carried out on rabbits and guinea pigs and in healthy human volunteers showed no sensitization and edema on the skin after 72 h of application. Results: The results of present study revealed that the prepared medicated sticks of Androgaphis Paniculata are convenient, equally effective, without any contamination chances on the application and free from skin irritation. Conclusion: The present work is a unique piece of contribution to the drug industry. The results will be useful to industry R&D for further investigations. The continuation of these work clinical studies is in progress.

scholarly journals Quantitatively immunological characterization of mogamulizumab skin disorders in ATL patients

2019 ◽  
Vol 2 (4) ◽  
pp. 102-107 ◽  
Author(s):  
Asahi Ito ◽  
Yui Suzuki ◽  
Ayako Masaki ◽  
Shinichiro Yoshida ◽  
Hitoshi Suzushima ◽  
...  
Keyword(s):  
Skin Disorders ◽  
Immunological Characterization
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