Abstract
Introduction: The purpose of this paper is to evaluate the efficacy and safety of extracorporeal shockwave therapy for Diabetic foot ulcers.Methods and analysis: The databases of China Science and Technology Journal Database, PubMed, EMBASE, Ovid MEDLINE, Web of Science, Embase, Cochrane Central Registry of Controlled Trials and China National Knowledge Infrastructure Database were searched to find the relevant studies. Keywords included the shockwave therapy, diabetic ulcers and related terms. References identified through the electronic search were screened, the data were extracted, and the methodological quality of the included studies was assessed. The meta-analysis was performed for the following outcomes: closure of diabetic foot ulcers, ulcer healing rate, ulcer healing time, ulcer recurrence rate, pain, Participant health-related quality of life/health score, hospital charges and amputation. Two authors independently screened search results, extracted data and appraised studies using the Cochrane risk of bias tool.Ethics and dissemination: The protocol of this systematic review (SR) does not require ethical approval because it does not involve humans. We will publish this article in peer-reviewed journals and presented at relevant conferences.PROSPERO and INPLASY registration number: CRD42020176959 ; INPLASY2020110001
Extracorporeal shockwave therapy in diabetic foot ulcers