scholarly journals Off-pump surgery does not reduce stroke, compared with results of on-pump coronary artery bypass grafting: A meta-analysis of randomized clinical trials

2007 ◽  
Vol 134 (4) ◽  
pp. 1059-1060 ◽  
Author(s):  
Hisato Takagi ◽  
Toshiyuki Tanabashi ◽  
Norikazu Kawai ◽  
Takuya Umemoto
Keyword(s):  
Clinical Trials ◽  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Off Pump ◽  
Pump Coronary Artery Bypass

scholarly journals Cognitive Dysfunction after Off-Pump versus On-Pump Coronary Artery Bypass Surgery: A Meta-Analysis

2012 ◽  
Vol 40 (3) ◽  
pp. 852-858 ◽  
Author(s):  
Jh Sun ◽  
Xy Wu ◽  
Wj Wang ◽  
Ll Jin
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Meta Analysis ◽  
Artery Bypass ◽  
Controlled Trials ◽  
Bypass Grafting ◽  
Off Pump ◽  
Randomized Controlled ◽  
Pump Coronary Artery Bypass

OBJECTIVE: A meta-analysis to compare the incidence of postoperative cognitive dysfunction (POCD) following off-pump coronary artery bypass grafting (OPCAB) versus after conventional coronary artery bypass grafting (CABG). METHODS: A systematic search of the Medline®, EMBASE® and Cochrane Library databases was performed to identify randomized controlled trials published until the end of November 2011. Data were analysed using RevMan version 5.0 software. RESULTS: The literature search identified 13 randomized controlled trials which included a total of 2326 cases. Meta-analysis found that the incidence of POCD was significantly higher following CABG than after OPCAB during the perioperative period (1 – 2 weeks) and at 3 months postsurgery. There were no significant between-group differences at 6 or 12 months postsurgery. CONCLUSIONS: Compared with CABG, OPCAB was found to be associated with a reduced incidence of early-stage POCD. Caution must be taken when interpreting these findings because of limitations in the available data.

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