The role of meibography in ocular surface diagnostics: A review

2020 ◽  
Author(s):  
Fredrik Fineide ◽  
Reiko Arita ◽  
Tor P. Utheim
Keyword(s):  
Ocular Surface ◽  
Surface Diagnostics

scholarly journals The role of Th17 immunity in chronic ocular surface disorders

2020 ◽  
Author(s):  
Nai-Wen Fan ◽  
Thomas H. Dohlman ◽  
William Foulsham ◽  
Matthew McSoley ◽  
Rohan Bir Singh ◽  
...  
Keyword(s):  
Ocular Surface

scholarly journals Tear ATG5 as a Potential Novel Biomarker in the Diagnosis of Sjögren Syndrome

Diagnostics ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 71
Author(s):  
Yong-Soo Byun ◽  
Hyun Jung Lee ◽  
Soojung Shin ◽  
Moon Young Choi ◽  
Hyung-Seung Kim ◽  
...  
Keyword(s):  
Ocular Surface ◽  
Area Under The Curve ◽  
Sjögren Syndrome ◽  
Sjogren Syndrome ◽  
Ocular Surface Disease Index ◽  
Dry Eyes ◽  
Potential Biomarker ◽  
Surface Staining ◽  
Breakup Time

Autophagy has been suggested to have an important role in the pathogenesis of Sjögren syndrome (SS). We previously identified that autophagy related 5 (ATG5) was elevated in the tear and conjunctival epithelial cells of SS dry eyes (DE) compared to non-SS DE. The purpose of this study was to investigate the role of tear ATG5 as a potential biomarker in the diagnosis of SS. To confirm this hypothesis, we evaluated the tear ATG5 concentration, and other ocular tests (Schirmer I, tear breakup time (TBUT), ocular surface staining (OSS) score, ocular surface disease index (OSDI)) in SS and non-DE, and compared their diagnostic performance to discriminate SS from non-SS DE. Tear ATG5 showed the greatest area under the curve (AUC = 0.984; 95% CI, 0.930 to 0.999) among the tests, and a 94.6% sensitivity and 93.6% specificity at a cutoff value of >4.0 ng/mL/μg. Our data demonstrated that tear ATG5 may be helpful as an ocular biomarker to diagnose and assess SS. In the future, the diagnostic power of tear ATG for SS should be validated.

The role of imaging technologies for ocular surface tumors

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Nandini Venkateswaran ◽  
Wathanee Sripawadkul ◽  
Carol L. Karp
Keyword(s):  
Ocular Surface ◽  
Imaging Technologies

Reconsidering the central role of mucins in dry eye and ocular surface diseases

2019 ◽  
Vol 71 ◽  
pp. 68-87 ◽  
Author(s):  
Christophe Baudouin ◽  
Maurizio Rolando ◽  
Jose M. Benitez Del Castillo ◽  
Elisabeth M. Messmer ◽  
Francisco C. Figueiredo ◽  
...  
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Ocular Surface Diseases

scholarly journals Role of impression cytology in ocular surface disorders

2020 ◽  
Vol 6 (1) ◽  
pp. 42-47
Author(s):  
Rupali Maheshgauri ◽  
Aishwarya Thakre ◽  
Manvi Aggarwal ◽  
Priyanka Mantri ◽  
Asim Naik
Keyword(s):  
Ocular Surface ◽  
Impression Cytology

Ocular Surface Disease and the Role of Preservatives in Glaucoma Medications*

Glaucoma ◽  
2015 ◽  
pp. 593-597 ◽  
Author(s):  
Sabita M Ittoop ◽  
Leonard K Seibold ◽  
Malik Y Kahook
Keyword(s):  
Ocular Surface ◽  
Ocular Surface Disease

scholarly journals The Role of SKQ1 (Visomitin) in Inflammation and Wound Healing of the Ocular Surface

2018 ◽  
Vol 8 (1) ◽  
pp. 63-73 ◽  
Author(s):  
Yi Wei ◽  
Andrew Troger ◽  
Viola Spahiu ◽  
Natalia Perekhvatova ◽  
Maxim Skulachev ◽  
...  
Keyword(s):  
Wound Healing ◽  
Ocular Surface

scholarly journals The Role of Multisystem Disease in Composition of Autologous Serum tears and ocular surface symptom improvement

2020 ◽  
Vol 18 (3) ◽  
pp. 499-504
Author(s):  
Madeline Ripa ◽  
Sayena Jabbehdari ◽  
Ghasem Yazdanpanah ◽  
Emoke Lukacs ◽  
Brandon Karcher ◽  
...  
Keyword(s):  
Ocular Surface ◽  
Autologous Serum ◽  
Symptom Improvement ◽  
Multisystem Disease
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