Involvement of P2X7 receptors in retinal ganglion cell death after optic nerve crush injury in rats

2013 ◽  
Vol 534 ◽  
pp. 237-241 ◽  
Author(s):  
Keigo Kakurai ◽  
Tetsuya Sugiyama ◽  
Takuji Kurimoto ◽  
Hidehiro Oku ◽  
Tsunehiko Ikeda
Keyword(s):  
Cell Death ◽  
Optic Nerve ◽  
Ganglion Cell ◽  
Optic Nerve Crush ◽  
Retinal Ganglion ◽  
P2x7 Receptors ◽  
Nerve Crush ◽  
Retinal Ganglion Cell Death ◽  
Ganglion Cell Death ◽  
Nerve Crush Injury

scholarly journals Rgcs1, a dominant QTL that affects retinal ganglion cell death after optic nerve crush in mice

2008 ◽  
Vol 9 (1) ◽  
pp. 74 ◽  
Author(s):  
Joel A Dietz ◽  
Yan Li ◽  
Lisa M Chung ◽  
Brian S Yandell ◽  
Cassandra L Schlamp ◽  
...  
Keyword(s):  
Cell Death ◽  
Optic Nerve ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Optic Nerve Crush ◽  
Retinal Ganglion ◽  
Nerve Crush ◽  
Retinal Ganglion Cell Death ◽  
Ganglion Cell Death

Phenytoin Blocks Retinal Ganglion Cell Death After Partial Optic Nerve Crush

2002 ◽  
Vol 74 (6) ◽  
pp. 747-752 ◽  
Author(s):  
Rita Naskar ◽  
Kristine Quinto ◽  
Ilka Romann ◽  
Frank Schuettauf ◽  
David Zurakowski
Keyword(s):  
Cell Death ◽  
Optic Nerve ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Optic Nerve Crush ◽  
Retinal Ganglion ◽  
Nerve Crush ◽  
Retinal Ganglion Cell Death ◽  
Ganglion Cell Death

Different functional susceptibilities of mouse retinal ganglion cell subtypes to optic nerve crush injury

2017 ◽  
Vol 162 ◽  
pp. 97-103 ◽  
Author(s):  
Zhen Puyang ◽  
Hai-Qing Gong ◽  
Shi-Gang He ◽  
John B. Troy ◽  
Xiaorong Liu ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Crush Injury ◽  
Optic Nerve Crush ◽  
Retinal Ganglion ◽  
Nerve Crush ◽  
Nerve Crush Injury

A second episode of ganglion cell death takes place when an optic nerve regenerates for a second time in the frog

1993 ◽  
Vol 10 (2) ◽  
pp. 297-301 ◽  
Author(s):  
L. D. Beazley ◽  
J.E. Darby
Keyword(s):  
Cell Death ◽  
Optic Nerve ◽  
Ganglion Cell ◽  
Ganglion Cells ◽  
Cresyl Violet ◽  
Retinal Ganglion ◽  
Nerve Crush ◽  
Optic Nerve Regeneration ◽  
Ability To Regenerate ◽  
Ganglion Cell Death

AbstractWe have previously reported that during optic nerve regeneration in the frog, 30–40% of retinal ganglion cells die, the loss being complete within 10 weeks. In the present study, we crushed the optic nerve, waited 10 weeks, and then recrushed the nerve at the same site. Retinae were examined 10 weeks later. We estimated ganglion cell numbers from cresyl-violet-stained wholemounts and found a fall of 53% compared to normals. The loss was significantly greater than the losses of 36% and 35%, respectively, in frogs which received a single optic nerve crush and were examined 10 or 20–24 weeks later. The results indicate that a second episode of ganglion cell death took place when the optic nerve regenerated a second time. We conclude that ganglion cells in the frog are not comprised of two subpopulations, only one of which intrinsically possesses the ability to regenerate.

Sign in / Sign up

Export Citation Format

Share Document