S-Adenosylhomocysteine increases β-amyloid formation in BV-2 microglial cells by increased expressions of β-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters

2009 ◽  
Vol 30 (4) ◽  
pp. 622-627 ◽  
Author(s):  
Hung-Chi Lin ◽  
Huei-Min Hsieh ◽  
Yu-Hsuan Chen ◽  
Miao-Lin Hu
Keyword(s):  
Amyloid Precursor Protein ◽  
Precursor Protein ◽  
Microglial Cells ◽  
Presenilin 1 ◽  
Amyloid Formation ◽  
Gene Promoters ◽  
Β Amyloid

scholarly journals Intracellular Trafficking of Presenilin 1 Is Regulated by β-Amyloid Precursor Protein and Phospholipase D1

2009 ◽  
Vol 284 (18) ◽  
pp. 12145-12152 ◽  
Author(s):  
Yun Liu ◽  
Yun-wu Zhang ◽  
Xin Wang ◽  
Han Zhang ◽  
Xiaoqing You ◽  
...  
Keyword(s):  
Amyloid Precursor Protein ◽  
Intracellular Trafficking ◽  
Precursor Protein ◽  
Presenilin 1 ◽  
Phospholipase D1 ◽  
Β Amyloid

Reelin in plaques of β-amyloid precursor protein and presenilin-1 double-transgenic mice

2001 ◽  
Vol 316 (3) ◽  
pp. 145-148 ◽  
Author(s):  
Oliver Wirths ◽  
Gerd Multhaup ◽  
Christian Czech ◽  
Véronique Blanchard ◽  
Günter Tremp ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Amyloid Precursor Protein ◽  
Precursor Protein ◽  
Presenilin 1 ◽  
Β Amyloid ◽  
Double Transgenic Mice

Presenilin 1 Regulates the Processing of β-Amyloid Precursor Protein C-Terminal Fragments and the Generation of Amyloid β-Protein in Endoplasmic Reticulum and Golgi†

Biochemistry ◽  
1998 ◽  
Vol 37 (47) ◽  
pp. 16465-16471 ◽  
Author(s):  
Weiming Xia ◽  
Jimin Zhang ◽  
Beth L. Ostaszewski ◽  
William Taylor Kimberly ◽  
Peter Seubert ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Amyloid Precursor Protein ◽  
Protein C ◽  
Amyloid Β ◽  
Precursor Protein ◽  
Presenilin 1 ◽  
Amyloid Β Protein ◽  
Β Protein ◽  
Β Amyloid

Intraneuronal Aβ accumulation precedes plaque formation in β-amyloid precursor protein and presenilin-1 double-transgenic mice

2001 ◽  
Vol 306 (1-2) ◽  
pp. 116-120 ◽  
Author(s):  
Oliver Wirths ◽  
Gerd Multhaup ◽  
Christian Czech ◽  
Véronique Blanchard ◽  
Saliha Moussaoui ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Amyloid Precursor Protein ◽  
Plaque Formation ◽  
Precursor Protein ◽  
Presenilin 1 ◽  
Β Amyloid ◽  
Double Transgenic Mice ◽  
Intraneuronal Aβ

scholarly journals Enhanced accumulation of phosphorylated α-synuclein in double transgenic mice expressing mutant β-amyloid precursor protein and presenilin-1

2007 ◽  
Vol 85 (10) ◽  
pp. 2246-2252 ◽  
Author(s):  
Tomoko Kurata ◽  
Takeshi Kawarabayashi ◽  
Tetsuro Murakami ◽  
Kazunori Miyazaki ◽  
Nobutoshi Morimoto ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Amyloid Precursor Protein ◽  
Precursor Protein ◽  
Presenilin 1 ◽  
Β Amyloid ◽  
Double Transgenic Mice

Presenilin-1 differentially facilitates endoproteolysis of the β-amyloid precursor protein and Notch

2000 ◽  
Vol 2 (4) ◽  
pp. 205-211 ◽  
Author(s):  
Anja Capell ◽  
Harald Steiner ◽  
Helmut Romig ◽  
Simone Keck ◽  
Miriam Baader ◽  
...  
Keyword(s):  
Amyloid Precursor Protein ◽  
Precursor Protein ◽  
Presenilin 1 ◽  
Β Amyloid
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