Intravitreal Tissue Plasminogen Activator, Ranibizumab, and Gas Injection for Submacular Hemorrhage in Polypoidal Choroidal Vasculopathy

Ophthalmology ◽  
2016 ◽  
Vol 123 (6) ◽  
pp. 1278-1286 ◽  
Author(s):  
Yorihisa Kitagawa ◽  
Hiroyuki Shimada ◽  
Ryusaburo Mori ◽  
Kouji Tanaka ◽  
Mitsuko Yuzawa
Keyword(s):  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Polypoidal Choroidal Vasculopathy ◽  
Gas Injection ◽  
Submacular Hemorrhage ◽  
Tissue Plasminogen ◽  
Choroidal Vasculopathy

Management of submacular hemorrhage by tissue plasminogen activator and SF6 gas injection

1999 ◽  
Vol 96 (10) ◽  
pp. 643-647 ◽  
Author(s):  
Petra Meier ◽  
Christian Zeumer ◽  
Claudia Jochmann ◽  
Peter Wiedemann
Keyword(s):  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Gas Injection ◽  
Submacular Hemorrhage ◽  
Tissue Plasminogen

scholarly journals Intravitreal tPA Injection and Pneumatic Displacement for Submacular Hemorrhage in a 10-Year-Old Child

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Takayuki Tsuyama ◽  
Hiroshi Hirose ◽  
Tomohiro Hattori
Keyword(s):  
Visual Acuity ◽  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Gas Injection ◽  
Age Related Macular Degeneration ◽  
Submacular Hemorrhage ◽  
Age Related ◽  
Choroidal Rupture ◽  
Tissue Plasminogen ◽  
Pneumatic Displacement

Background. Submacular hemorrhage can occur after blunt trauma to the eye. Intravitreal tissue plasminogen activator (tPA) and gas injection are often used for treatment and are effective for submacular hemorrhage caused by age-related macular degeneration. This report describes the clinical outcome in a child with submacular hemorrhage caused by traumatic choroidal rupture who underwent successful intravitreal tPA injection and pneumatic displacement.Case Presentation. A 10-year-old boy developed sudden decrease of vision and a central scotoma in his right eye after trauma. Submacular hemorrhage was found in the eye. Visual acuity was 20/70 OD. Tissue plasminogen activator (12.5 μg in 0.05 mL) and 0.3 mL of pure sulfur hexafluoride were injected into the vitreous cavity under general anesthesia. After surgery, the patient was instructed to maintain a prone position. Displacement of the submacular hemorrhage from the fovea revealed a choroidal rupture, presumed to be the cause of the hemorrhage. After 4 months of follow-up, visual acuity was restored and final visual acuity is 20/16.Conclusion. Intravitreal tPA and gas injection can be an effective treatment for children with submacular hemorrhage.

MANAGEMENT OF SUBMACULAR HEMORRHAGE WITH INTRAVITREAL INJECTION OF TISSUE PLASMINOGEN ACTIVATOR AND EXPANSILE GAS

Retina ◽  
2007 ◽  
Vol 27 (3) ◽  
pp. 321-328 ◽  
Author(s):  
CHRISTINE Y. CHEN ◽  
CLAIRE HOOPER ◽  
DANIEL CHIU ◽  
MATTHEW CHAMBERLAIN ◽  
NIRAL KARIA ◽  
...  
Keyword(s):  
Intravitreal Injection ◽  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Submacular Hemorrhage ◽  
Tissue Plasminogen
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