What governs marine fouling assemblages on chemically-active antifouling coatings?

2022 ◽  
Vol 164 ◽  
pp. 106701
Christine Bressy ◽  
Jean-François Briand ◽  
Sandra Lafond ◽  
Romain Davy ◽  
Florence Mazeas ◽  
2007 ◽  
Vol 28 (3) ◽  
pp. 368-376 ◽  
Heather Sugden ◽  
Rafael Panusch ◽  
Mark Lenz ◽  
Martin Wahl ◽  
Jeremy C. Thomason

2020 ◽  
Vol 150 ◽  
pp. 110768 ◽  
J. Tempesti ◽  
J. Langeneck ◽  
F. Maltagliati ◽  
A. Castelli

2021 ◽  
pp. 110578
Esther Roeven ◽  
Luc Scheres ◽  
Maarten M. J. Smulders ◽  
Han Zuilhof

Marine Drugs ◽  
2020 ◽  
Vol 19 (1) ◽  
pp. 5
Daniela Pereira ◽  
Catarina Gonçalves ◽  
Beatriz T. Martins ◽  
Andreia Palmeira ◽  
Vitor Vasconcelos ◽  

Over the last decades, antifouling coatings containing biocidal compounds as active ingredients were used to prevent biofouling, and eco-friendly alternatives are needed. Previous research from our group showed that polymethoxylated chalcones and glycosylated flavones obtained by synthesis displayed antifouling activity with low toxicity. In this work, ten new polymethoxylated flavones and chalcones were synthesized for the first time, including eight with a triazole moiety. Eight known flavones and chalcones were also synthesized and tested in order to construct a quantitative structure-activity relationship (QSAR) model for these compounds. Three different antifouling profiles were found: three compounds (1b, 11a and 11b) exhibited anti-settlement activity against a macrofouling species (Mytilus galloprovincialis), two compounds (6a and 6b) exhibited inhibitory activity against the biofilm-forming marine bacteria Roseobacter litoralis and one compound (7b) exhibited activity against both mussel larvae and microalgae Navicula sp. Hydrogen bonding acceptor ability of the molecule was the most significant descriptor contributing positively to the mussel larvae anti-settlement activity and, in fact, the triazolyl glycosylated chalcone 7b was the most potent compound against this species. The most promising compounds were not toxic to Artemia salina, highlighting the importance of pursuing the development of new synthetic antifouling agents as an ecofriendly and sustainable alternative for the marine industry.

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