Primary splenic marginal zone lymphoma with florid granulomatous reaction—A case report and review of literature

2007 ◽  
Vol 203 (4) ◽  
pp. 239-243 ◽  
Author(s):  
M.T. Manipadam ◽  
A. Viswabandya ◽  
A. Srivastava
2012 ◽  
Vol 93 (5) ◽  
pp. 843-846
Author(s):  
N A Romanenko ◽  
S S Bessmeltsev ◽  
K M Abdulkadyrov

A case report of a patients with splenic marginal zone lymphoma, in whom clinical remission was initially achieved by 5 continuous courses of combined treatment with fludarabine 25 mg/m2 and cyclophosphamide 350 mg/m2 at days 1-3. Nevertheless, 6 months after patient developed a clinical picture of Evans syndrome, characterized by severe hemolytic anemia, thrombocytopenia and neutropenia. Corticosteroid treatment accompanied by blood transfusion was initiated, the effect was marginal and short-lasting. Switch to rituximab monotherapy allowed to archieve complete clinical and hematological remission with full blood count parameters reversal.


2015 ◽  
Vol 62 (1) ◽  
pp. 234-237 ◽  
Author(s):  
Roberto Rossotti ◽  
Giovanna Travi ◽  
Annamaria Pazzi ◽  
Chiara Baiguera ◽  
Enrica Morra ◽  
...  

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