Does Motion Management Technique for Lung SBRT Influence Local Control? A Single Institutional Experience Comparing Abdominal Compression to Breath-Hold Technique

Author(s):  
Senthilkumar Gandhidasan ◽  
Neil M. Woody ◽  
Kevin L. Stephans ◽  
Gregory M.M. Videtic
2022 ◽  
pp. 100895
Author(s):  
Kaestner Lena ◽  
Abo-Madyan Yasser ◽  
Huber Lena ◽  
Spaniol Manon ◽  
Siebenlist Kerstin ◽  
...  

2021 ◽  
Vol 23 (Supplement_6) ◽  
pp. vi41-vi41
Author(s):  
Isabela Pena-Pino ◽  
Jun Ma ◽  
Yusuki Hori ◽  
Elena Fomchenko ◽  
Kathryn Dusenbery ◽  
...  

Abstract INTRODUCTION In independent clinical trials, ~30% of brain metastases recur locally after radiosurgery (BMRS). For these lesions, treatment with stereotactic laser ablation (SLA, also known as laser interstitial thermal therapy (LITT)) alone achieves a 12-month local control (LC12) of 54-85% while repeat SRS achieved LC12 of 54-79%. Here, we report favorable outcomes for BMRS treated with SLA followed by consolidation radiosurgery (SLA/cSRS). METHODS Clinical outcome of 18 patients with 19 histologically confirmed BMRS treated with SLA followed by consolidation SRS and >3 months follow-up were collected retrospectively across three institutions. Local control was defined as stability or decrease in contrast-enhancing (CE) and FLAIR volume. RESULTS SLA achieved ablation of 73-100% of the BMRS CE volumes. Consolidation hypo-fractionated radiosurgery (5 Gy x 5 or 6 Gy x 5) was carried out 16-40 days post-SLA (median of 26 days). With a median follow-up of 185 days (range: 93-1367 days) and median overall survival (OS) of 185 days (range: 99-1367 days), 100% LC12 was achieved. 13/18 (72%) patients that required steroid therapy prior to SLA/cSRS were successfully weaned off steroid by three months post-SLA/cSRS. Post-SLA, KPS declined for 3/19 (16%) patients and improved for 1/19 (5%) patients. No KPS changes occurred subsequent to consolidation SRS. There were no 30-day mortalities or wound complications. Two patients required re-admission within 30 days of SRS (severe headache that resolved with steroid therapy (n=1) and new-onset seizure (n=1)). Except for two patients who suffered histologically confirmed, local failure at 649 and 899 days, all other patients are either alive (n=6) or died from systemic disease progression (n=10). None of the treated patients developed symptomatic radiation necrosis. CONCLUSIONS This collaborative institutional experience support efficacy and safety of SLA followed by consolidation SRS as a treatment for BMRS. The treatment strategy warrants further investigations.


2012 ◽  
Vol 84 (3) ◽  
pp. S748-S749
Author(s):  
C.Y. Shang ◽  
M. Kasper ◽  
T.R. Williams ◽  
R. Benda ◽  
J.C. Shope ◽  
...  
Keyword(s):  
Fdg Pet ◽  

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
P. Freislederer ◽  
M. Kügele ◽  
M. Öllers ◽  
A. Swinnen ◽  
T.-O. Sauer ◽  
...  

Abstract The growing acceptance and recognition of Surface Guided Radiation Therapy (SGRT) as a promising imaging technique has supported its recent spread in a large number of radiation oncology facilities. Although this technology is not new, many aspects of it have only recently been exploited. This review focuses on the latest SGRT developments, both in the field of general clinical applications and special techniques. SGRT has a wide range of applications, including patient positioning with real-time feedback, patient monitoring throughout the treatment fraction, and motion management (as beam-gating in free-breathing or deep-inspiration breath-hold). Special radiotherapy modalities such as accelerated partial breast irradiation, particle radiotherapy, and pediatrics are the most recent SGRT developments. The fact that SGRT is nowadays used at various body sites has resulted in the need to adapt SGRT workflows to each body site. Current SGRT applications range from traditional breast irradiation, to thoracic, abdominal, or pelvic tumor sites, and include intracranial localizations. Following the latest SGRT applications and their specifications/requirements, a stricter quality assurance program needs to be ensured. Recent publications highlight the need to adapt quality assurance to the radiotherapy equipment type, SGRT technology, anatomic treatment sites, and clinical workflows, which results in a complex and extensive set of tests. Moreover, this review gives an outlook on the leading research trends. In particular, the potential to use deformable surfaces as motion surrogates, to use SGRT to detect anatomical variations along the treatment course, and to help in the establishment of personalized patient treatment (optimized margins and motion management strategies) are increasingly important research topics. SGRT is also emerging in the field of patient safety and integrates measures to reduce common radiotherapeutic risk events (e.g. facial and treatment accessories recognition). This review covers the latest clinical practices of SGRT and provides an outlook on potential applications of this imaging technique. It is intended to provide guidance for new users during the implementation, while triggering experienced users to further explore SGRT applications.


2019 ◽  
Vol 141 ◽  
pp. S23
Author(s):  
R. Kaul ◽  
R.K. Munjal ◽  
H. Malhotra ◽  
R. Kumar ◽  
D. Kumar

2011 ◽  
Vol 38 (6Part1) ◽  
pp. 3114-3124 ◽  
Author(s):  
Yang-Kyun Park ◽  
Siyong Kim ◽  
Hwiyoung Kim ◽  
II Han Kim ◽  
Kunwoo Lee ◽  
...  

2015 ◽  
Vol 42 (6Part14) ◽  
pp. 3372-3372
Author(s):  
H Liu ◽  
M Manning ◽  
B Sintay ◽  
J Maurer ◽  
L Hayes ◽  
...  

2018 ◽  
Vol 56 ◽  
pp. 68-69
Author(s):  
S. Cilla ◽  
A. Ianiro ◽  
M. Craus ◽  
P. Viola ◽  
G. Macchia ◽  
...  

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