Separation and Purification of Penicillin G from fermentation broth by solvent sublation

2009 ◽  
Vol 65 (2) ◽  
pp. 228-231 ◽  
Author(s):  
P.Y. Bi ◽  
H.R. Dong ◽  
Q.Z. Guo
Keyword(s):  
Fermentation Broth ◽  
Penicillin G ◽  
Separation And Purification

Recent advances in the separation and purification of lactic acid from fermentation broth

2021 ◽  
Vol 104 ◽  
pp. 142-151
Author(s):  
Chenglong Li ◽  
Ming Gao ◽  
Wenbin Zhu ◽  
Nuohan Wang ◽  
Xiaoyu Ma ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Fermentation Broth ◽  
Separation And Purification ◽  
Recent Advances

Process integration for production of 6-aminnopenicillanic acid from penicillin G fermentation broth

2006 ◽  
Vol 41 (3) ◽  
pp. 571-574 ◽  
Author(s):  
Shufeng Shen ◽  
Zhidong Chang ◽  
Xinghua Sun ◽  
Huizhou Liu
Keyword(s):  
Process Integration ◽  
Fermentation Broth ◽  
Penicillin G

Separation and purification of l-methionine from E. coli fermentation broth by macroporous resin chromatography

2019 ◽  
Vol 1110-1111 ◽  
pp. 108-115 ◽  
Author(s):  
Neng Xiong ◽  
Ru Yu ◽  
Tao Chen ◽  
Ya-Ping Xue ◽  
Zhi-Qiang Liu ◽  
...  
Keyword(s):  
Fermentation Broth ◽  
Separation And Purification ◽  
Macroporous Resin ◽  
E Coli

Separation and purification of three, four, and five carbon diamines from fermentation broth

2019 ◽  
Vol 196 ◽  
pp. 324-332 ◽  
Author(s):  
Jong An Lee ◽  
Jung Ho Ahn ◽  
Inho Kim ◽  
Sheng Li ◽  
Sang Yup Lee
Keyword(s):  
Fermentation Broth ◽  
Separation And Purification

Separation and Purification of Lactic Acid from Fermentation Broth Using Membrane-Integrated Separation Processes

2017 ◽  
Vol 56 (29) ◽  
pp. 8301-8310 ◽  
Author(s):  
Hee Dae Lee ◽  
Min Yong Lee ◽  
Yoon Sung Hwang ◽  
Young Hoon Cho ◽  
Hyo Won Kim ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Fermentation Broth ◽  
Separation And Purification ◽  
Separation Processes

scholarly journals SEPARATION OF PENICILLIN G FROM FERMENTATION BROTH BY EMULSION LIQUID MEMBRANE TECHNIQUE

2010 ◽  
Vol 10 (1) ◽  
pp. 46-50
Author(s):  
Imam Santoso ◽  
Bachri Amran ◽  
Apriliana Laily Fitri
Keyword(s):  
Phenylacetic Acid ◽  
Liquid Membrane ◽  
Fermentation Broth ◽  
Penicillin G ◽  
Optimal Conditions ◽  
Phase Volume ◽  
Emulsion Liquid Membrane ◽  
Internal Phase ◽  
Membrane Technique ◽  
External Phase

The separation of penicillin G from fermentation broth can be done by emulsion liquid membrane technique. The aim of this research is to establish the optimal conditions for the extraction and separation of penicillin G using emulsion liquid membrane technique. The optimal conditions were found to be at ratio of internal phase volume to membrane phase volume of 1:1 ; time of making emulsion, 1 min ; emulsion contact rate, 300 rpm; rate of stirring of emulsion, 2000 rpm ; rest time of emulsion, 13 min; concentration of  penicillin G as external phase, 375 ppm; and concentration of surfactant, 5% (v/v). pH of internal phase is 8; pH of external phase 5; ratio of emulsion phase volume to external phase volume, 1:2 and concentration of carrier 2 mM. The concentration of penicillin G and phenylacetic acid from fermentation results were 24771 mg/L and 32675 mg/L. Extraction by emulsion liquid membrane technique gave the percentage of penicillin G 53.38% and phenylacetic acid 60.41%. The percentage phenylacetic acid which is still higher (60.41%) indicated that the penicillin G could not completely be separated from phenylacetic acid by emulsion liquid membrane technique.   Keywords: penicillin G, fermentation, emulsion liquid membrane technique

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