Long-term therapeutic efficacy of oral appliances in treatment of obstructive sleep apnea–hypopnea syndrome

2015 ◽  
Vol 16 ◽  
pp. S80
Author(s):  
X. Gong ◽  
J. Zhang ◽  
Y. Zhao ◽  
X. Gao
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Therapeutic Efficacy ◽  
Oral Appliances ◽  
Obstructive Sleep ◽  
Hypopnea Syndrome

scholarly journals Long-term therapeutic efficacy of oral appliances in treatment of obstructive sleep apnea-hypopnea syndrome

2012 ◽  
Vol 83 (4) ◽  
pp. 653-658 ◽  
Author(s):  
Xu Gong ◽  
Jingjing Zhang ◽  
Ying Zhao ◽  
Xuemei Gao
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Side Effects ◽  
Term Therapy ◽  
Cephalometric Analysis ◽  
Oral Appliances ◽  
Obstructive Sleep ◽  
Hypopnea Syndrome

ABSTRACT Objective: To investigate the long-term efficacy and safety of oral appliances (OAs) in treating obstructive sleep apnea-hypopnea syndrome (OSAHS) by length of treatment. Materials and Methods: This is a retrospective study to review the usage of OAs in Chinese OSAHS patients in recent decades. Ninety-four valid questionnaires were returned by 412 patients with OSAHS receiving OA treatment. Among the wearers, 22 agreed to follow-up polysomnography, and 25 agreed to follow-up cephalograms. Tolerance and side effects of OAs were assessed by a survey. Comparisons of efficacy were carried out between the initial and follow-up polysomnography measurements. Cephalometric analysis was used to investigate skeletal and occlusal changes to determine safety of the OAs. Results: The longest treatment extended to 147 months, with a median of 74 months (first and third quartiles, 30 and 99 months, respectively). Among the participants, 14.9% had been treated for more than 120 months. Side effects were temporary and relatively minimal and included tooth soreness (37.2%), dry mouth (33.0%), odd bite feeling (31.9%), and excess salivation (30.8%). Polysomnography proved that OAs remained effective for the treatment of OSAHS in the long term; initial Apnea-Hypopnea Index values were reduced from a median of 24.50 (quartiles, 14.65, 54.05) without the OA to 7.40 with the OA (2.12, 10.00), and follow-up median values were 25.55 without the OA (11.71, 43.65) and 4.25 with the OA (1.38, 7.70). Cephalometric analysis indicated mild and slow changes in the skeleton and occlusion after average treatment duration of 5 years. Conclusion: OAs provided effective and safe long-term therapy for patients with OSAHS. Follow-up supervision is recommended since long-term alterations take place, although these appear to be minimal.

Therapeutic Efficacy of Twin-Block and Fixed Oral Appliances in Patients with Obstructive Sleep Apnea Syndrome

2017 ◽  
Vol 28 (2) ◽  
pp. e830-e836 ◽  
Author(s):  
George Umemoto ◽  
Hideo Toyoshima ◽  
Yuji Yamaguchi ◽  
Naoko Aoyagi ◽  
Chikara Yoshimura ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Therapeutic Efficacy ◽  
Sleep Apnea Syndrome ◽  
Oral Appliances ◽  
Twin Block ◽  
Obstructive Sleep ◽  
Apnea Syndrome

scholarly journals Long Term Therapeutic Efficacy of a Soft Monobloc Mandibular Advancement Device in Adults with Obstructive Sleep Apnea

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Fabiana Ballanti ◽  
Salvatore Ranieri ◽  
Alberto Baldini ◽  
Paola Cozza
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Therapeutic Efficacy ◽  
Mandibular Advancement Device ◽  
Mandibular Advancement ◽  
Apnea Hypopnea Index ◽  
Stomatognathic System ◽  
Obstructive Sleep ◽  
T1 And T2

Aim. To evaluate the long term (48 months) therapeutic efficacy of a soft monobloc mandibular advancement device in adult patients with mild or moderate obstructive sleep apnea.Methods. The study population comprised 28 patients (6 female and 22 male, mean age52.2±6.8years) affected by obstructive sleep apnea. After a baseline medical and somnographic examination, a functional examination of the stomatognathic system, and a questionnaire focused on sleep-related qualities and a daytime somnolence, each patient received an individual device. Two follow-ups were made 6 months (T1) and 48 months (T2) after soft monobloc mandibular advancement device treatment had been initiated, and all initial examinations were repeated.Results. The statistical analysis showed a significant decrease in body mass index value between T1 and T2 (ρ= 0,012), an increase of Epworth sleepiness scale value between T1 and T2 (ρ= 0,012), and a significant improvement and decrease of apnea/hypopnea index between T0 and T1 (ρ= 0,010) and between T0 and T2 (ρ= 0,013).Conclusion. Treatment with the soft monobloc mandibular advancement device is a therapeutic solution with long term and stable effects (48 months) for patients suffering from mild or moderate obstructive sleep apnea.

scholarly journals Efficacy of Somnodent® Appliance Therapy in Moderate to Severe Obstructive Sleep Apnea Patients Somnodent® OAs for Moderate to Severe OSAHS

2021 ◽  
Vol 3 (3) ◽  
pp. 01-07
Author(s):  
Guillaume Buiret ◽  
Frederic Chidiac
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Reduction Rate ◽  
Oral Appliance ◽  
Dropout Rate ◽  
Apnea Hypopnea Index ◽  
Severe Obstructive Sleep Apnea ◽  
Oral Appliances ◽  
Obstructive Sleep ◽  
Hypopnea Syndrome

Objective: Oral appliances are one of the treatments of obstructive sleep apnea hypopnea syndrome. The main objective of the study was to determine the efficacy of the Somnodent® oral appliance on Apnea-Hypopnea Index. The secondary objective was to measure the efficacy on other oxymetric parameters and to determine its tolerance and dropout rate. Methods: Efficacy results of the oral appliances based on the apnea hypopnea index, the oxygen desaturation index and the lower oxygen saturation reduction, appliance complications and dropout rates were retrospectively collected from 25 patients with a moderate to severe obstructive sleep apnea hypopnea syndrome treated by a Somnodent® oral appliance. The procedure was entirely performed by otolaryngologists. Results: The AHI with OA was more significantly reduced in patients with a higher initial apnea hypopnea index and a higher initial body mass index but reduction was not related to age and not proportional to degree of mandibular advancement. The 50%-AHI reduction rate after OA was 55.6%, the AHI ≤5/h rate after OA was 22.2%. The OA significantly reduced the mean apnea-hypopnea index (-14.3/h, p<10-5). No patient had his AHI increased with oral appliance. One patient stopped using OA mainly because of nausea. Conclusions: Somnodent® is an effective and well-tolerated treatment for moderate to severe obstructive sleep apnea hypopnea syndrome.

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