Long-term clinical and radiologic results of small cerebral aneurysms embolized with 1 or 2 detachable coils

2006 ◽  
Vol 66 (5) ◽  
pp. 507-512 ◽  
Author(s):  
Hyon-Jo Kwon ◽  
Jun-Bum Park ◽  
Yang Kwon ◽  
Jae-Sung Ahn ◽  
Byung-Duk Kwun
Keyword(s):  
Cerebral Aneurysms ◽  
Detachable Coils

The Role of Blood Impulse in Cerebral Aneurysm Coil Compaction: Effect of Aneurysm Neck Size

2003 ◽  
Author(s):  
Baruch B. Lieber ◽  
Chander Sadasivan ◽  
Matthew J. Gounis ◽  
Ajay K. Wakhloo
Keyword(s):  
Cerebral Aneurysms ◽  
Momentum Equation ◽  
Parent Vessel ◽  
Neck Size ◽  
Aneurysm Neck ◽  
Hemodynamic Forces ◽  
Sigmoid Curve ◽  
Detachable Coils ◽  
Aneurysm Volume

Endovascular occlusion of cerebral aneurysms with bare platinum detachable coils is now recognized as preferable to surgical clipping (ISUIA Group, 2003, ISAT Group, 2002, Bavinzski et al, 1995, Thornton et al, 2002). Dependent on coil packing density (the ratio of the coil volume deposited in an aneurysm to that of the aneurysm volume), aneurysm location, size and neck width, coil compaction with recanalization of the aneurysm remains in the long-term a major concern. The aneurysm neck size is reported to be the main predictor for aneurysm recanalization (Fernandez-Zubillaga et al, 1994). The forces exerted on the coil mass at the aneurysm neck due to blood pulsatility are larger for wide neck aneurysms as compared to small neck aneurysms (Bavinzski et al, 1995). However, impingement forces have not been evaluated. We evaluated the force impinging on the aneurysm neck in a simplified aneurysm (basilar top) geometry utilizing the impulse-momentum equation and Womersley’s flow. Maximum impingement force as a function of aneurysm neck to parent lumen diameter ratio varies as a sigmoid curve. Analysis of the hemodynamic forces affecting coil compaction in cerebral aneurysms shows that the coil mass at the aneurysm neck may be subjected to cyclic impulse impingement due to redirection of blood momentum. Orientation of the aneurysm neck and the main axis of the aneurysm in relation to the oncoming parent vessel flow may help clinicians predict the risk of coil compaction and the location of subsequent aneurysm recanalization.

Long-Term Results of Ruptured Cerebral Aneurysms Embolized in Acute Stage with Interlocking Detachable Coils

1997 ◽  
Vol 3 (2_suppl) ◽  
pp. 118-120
Author(s):  
H. Manabe ◽  
S. Fujita ◽  
K. Akasaka ◽  
S. Suzuki
Keyword(s):  
Cerebral Aneurysms ◽  
Critical Factor ◽  
Dissecting Aneurysm ◽  
Acute Stage ◽  
Saccular Aneurysm ◽  
Long Term Results ◽  
Complete Occlusion ◽  
Detachable Coils

We report on a series of eight patients presenting with SAH secondary to ruptured saccular (n=7) or dissecting (n=1) aneurysm, treated in the acute stage (within 14 days) by embolization with interlocking detachable coils (IDCs) who survived at least 3 months following initial hemorrhage. Embolization resulted in complete occlusion in 2 of 7 cases of saccular aneurysm, 90–95% occlusion was obtained in the remaining 5 cases of saccular aneurysm. Proximal occlusion with intra-aneurysmal coil packing was achieved in 1 case of dissecting aneurysm. In all 5 cases with partial occlusion, follow-up angiograms taken 2–4 months after the embolization showed partial recanalization due to coil compaction, while no recanalization was recognized in cases with complete occlusion in follow-up angiograms at 5 and 9 months respectively. Clinical disability, at 9 months after the embolization was rated as none in 4 cases, moderate in 1, and severe in 1. Two patients died of re-rupture at 4 and 8 months respectively after the embolization. Of the other 3 cases with partial recanalization, 2 were retreated by re-embolization or surgical clipping, one has been followed clinically and angiographically. Histological findings of the re-ruptured aneurysm showed neither endothelialization of the aneurysmal orifice nor organization of the clot around the coils. Aneurysmal re-rupture secondary to coil compaction related recanalization remains a critical factor in long-term clinical outcome and prognosis.

scholarly journals Angiographic Follow-up of Embolization Using Guglielmi Detachable Coils for Cerebral Aneurysms

2003 ◽  
Vol 9 (1_suppl) ◽  
pp. 47-50 ◽  
Author(s):  
Y. Nakai ◽  
M. Sonobe ◽  
K. Sugita ◽  
Y. Matsumaru
Keyword(s):  
Morphological Changes ◽  
Cerebral Aneurysms ◽  
Guglielmi Detachable Coils ◽  
Complete Occlusion ◽  
Unruptured Aneurysms ◽  
Ruptured Aneurysms ◽  
Detachable Coils ◽  
Aneurysm Occlusion

The purpose of this study is to evaluate the mid or long-term angiographical stability of Guglielmi Detachable Coils (GDC) after embolization for cerebral aneurysms. Between march 1997 and november 2001, 164 aneurysms, including 116 ruptured and 48 unruptured aneurysms, were treated using GDC at Mito National Hospital. Cerebral angiograms over one month after embolization were obtained in 111 aneurysms, including 71 ruptured and 40 unruptured aneurysms. At the time of initial GDC embolization of the 71 ruptured aneurysms, complete occlusion was achieved in 31 aneurysms, neck remnant in 18 aneurysms, and body filling in 22 aneurysms. Morphological changes were observed in 26 aneurysms (37%) in follow-up. Progressive thrombosis was obtained in 12 out of 71 aneurysms, no changes were shown in 45, and recanalizations occurred in 14. In the initial embolization of the 40 unruptured aneurysms, complete occlusion was achieved in 15 aneurysms, neck remnant in five and body filling in 20 aneurysms respectively. Morphological changes were observed in 12 aneurysms (30%), in which 12 aneurysms showed progressive thrombosis and 28 aneurysms were unchanged. There were significant differences of the long-term angiographical stability between ruptured and unruptured aneurysms. Rigorous follow-up angiography is mandatory when complete aneurysm occlusion is not achieved in ruptured aneurysms.

scholarly journals Spontaneous Thrombosis of Significant Aneurysm Recanalization in the Long Term Follow-up of Coiled Aneurysms: Observation in Two Cases

2005 ◽  
Vol 11 (2) ◽  
pp. 167-171 ◽  
Author(s):  
I. Saatchi ◽  
U. Kerimoglu ◽  
C. Barbaros ◽  
T. Haziroln ◽  
S. Cekirge
Keyword(s):  
Endovascular Treatment ◽  
Treatment Strategies ◽  
Cerebral Aneurysms ◽  
Spontaneous Thrombosis ◽  
Long Term Follow Up ◽  
Detachable Coils ◽  
One Year ◽  
Control Angiography

Endovascular treatment of cerebral aneurysms with detachable coils has now been proved to be a superior alternative to open microsurgery in terms of survival free of disability at one year according to the recently published large randomized International Subaracnoid Aneurysm Trial (ISAT). However, aneurysm recanalization secondary to coil compaction is still the main problem of this technique observed in the follow-up period but treatment strategies for these regrowths are not yet well established. We present two interesting cases in which we observed a significant aneurysm recanalization at six month control angiography that was found to be spontaneously thrombosed in the late follow-up angiograms at the second and fifth years consecutively.

Early Clinical Outcome of Patients with Ruptured Cerebral Aneurysms Treated by Endovascular (GDC) or Microsurgical Techniques

1995 ◽  
Vol 1 (1) ◽  
pp. 19-27 ◽  
Author(s):  
B. Richling ◽  
G. Bavinzski ◽  
C. Gross ◽  
A. Gruber ◽  
M. Killer
Keyword(s):  
Clinical Outcome ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Cerebral Aneurysms ◽  
Guglielmi Detachable Coils ◽  
Early Results ◽  
Detachable Coils ◽  
Vienna Medical School ◽  
Microsurgical Techniques ◽  
Short Time

Over the past 3.5 years 220 patients with aneurysmal subarachnoid hemorrhage were treated in the Department of Neurosurgery University of Vienna Medical School using either endovascular techniques (Guglielmi Detachable Coils) or open craniotomy with aneurysm clipping. A retrospective analysis was undertaken to assess whether any difference in outcome could be correlated with the treatment choice. The patients were stratified as to 1) Hunt and Hess grade at time of treatment, 2) method of treatment, and 3) clinical outcome at 2–4 weeks following treatment. The outcomes in this population of patients were consistent with recent published series regardless of whether the aneurysms were treated with microvascular surgery or endovascular surgery. There was a trend toward better outcome in a relatively small sub-group of patients presenting as Hunt and Hess grade III who were treated by the endovascular method. Guglielmi detachable coils have been available for a relatively short time, and although early results are promising, the ultimate long-term efficacy of the coils will have to be assessed.

scholarly journals Retreatment of Cerebral Aneurysms after Guglielmi Detachable Coil Embolization

2004 ◽  
Vol 10 (1_suppl) ◽  
pp. 167-171 ◽  
Author(s):  
Y Matsumaru ◽  
H Sato ◽  
T Takigawa ◽  
M Okazaki ◽  
T Kamezaki ◽  
...  
Keyword(s):  
Cerebral Aneurysms ◽  
Parent Artery ◽  
Detachable Coil ◽  
Technical Improvement ◽  
Guglielmi Detachable Coil ◽  
Surgical Clip ◽  
Embolic Agents ◽  
Detachable Coils ◽  
Additional Therapy

Of 175 patients with 181 aneurysms initially treated with Guglielmi Detachable Coils (GDC), 25 were retreated. All retreatments except one were performed on previously ruptured aneurysms. Thirteen aneurysms were retreated because of recurrence, and 12 aneurysms were retreated to complete initial insufficient embolization. Sixteen patients underwent re-embolization and 9 patients were operated upon surgically. No complications related to the retreatment were experienced. We consider that repeat embolization should be attempted before considering surgical treatment in case that additional therapy is required. However, it is difficult to retreat aneurysms having wide necks. In regard to surgical clipping, aneurysms without a coil in the neck are easier to treat with primary clipping, whereas aneurysms with a coil mass in the neck are difficult to surgical clip. We have never used temporary clipping and coil extraction if the distance between the coil and the parent artery was wider than 2 mm. Emerging new embolic agents or devices and technical improvement might decrease the need for retreatment and increase long-term efficacy after endovascular treatment.

scholarly journals Long Term Angiographical Follow-up of Cerebral Aneurysms after Coil Embolization

2001 ◽  
Vol 7 (1_suppl) ◽  
pp. 149-154 ◽  
Author(s):  
Y. Kaku ◽  
K. Hayashi ◽  
M. Sawada ◽  
N. Sakai
Keyword(s):  
Special Reference ◽  
Coil Embolization ◽  
Cerebral Aneurysms ◽  
Complete Obliteration ◽  
Long Term Follow Up ◽  
Platinum Coils

We evaluated long-term angiographical follow-up of cerebral aneurysms treated with detachable platinum coils with special reference to the long-term morphological outcomes of incompletely obliterated aneurysms. Serial long-term follow-up cerebral angiograms (>1 year) were obtained in 47 cases out of 134 cases treated with GDCs or IDCs from 1994 to 1999. In 47 patients, intial angiographical results demonstrated ten complete aneurysmal occlusion, seven aneurysms with a small neck remnant, twenty aneurysms with body filling and ten aneurysms with both of neck remnant and body filling. In the ten completely obliterated aneurysms, follow-up angiograms revealed no aneurysmal recanalization. In seven aneurysms with neck remnant, three remained unchanged, four showed enlargement of contrast filling in the part of the neck of the aneurysm. In twenty aneurysms with body filling, five had developed into complete obliteration, three remained unchanged, 11 had recanalization, and one aneurysm displayed regrowth. In ten aneurysms with both of neck remnant and body filling, two remained unchanged, five had recanalization, and three aneurysms displayed regrowth. Long-term angiographical follow-up results are less satisfactory in cases involving incompletely obliterated lesions. A higher incidence of recanalizations were promoted in cases with neck remnant and/or body filling. Strict follow-up angiography is mandatory when a complete obliteration is not achieved.

scholarly journals MTI (Dendron) Variable Detachable Coils

2003 ◽  
Vol 9 (1) ◽  
pp. 47-52
Author(s):  
J. Thammaroj ◽  
V. Jayakrishnan ◽  
S. Lamin ◽  
S. Jenkins ◽  
E. Teasdale ◽  
...  
Keyword(s):  
Endovascular Treatment ◽  
Feasibility Study ◽  
Clinical Experience ◽  
Cerebral Aneurysms ◽  
Detachable Coils ◽  
Formed Part ◽  
Small Aneurysms ◽  
Initial Clinical Experience

We present our initial clinical experience of Dendron Variable Detachable System (VDS) coils, now Sapphire VDS from MTI, in the endovascular treatment of cerebral aneurysms. VDS coils, uniquely, can be detached at variable points along their length, allowing placement of as much or as little as desired of the coil within the aneurysm. Our ten patients formed part of a multicentre feasibility study. VDS coils were successfully deployed in all but one aneurysm. The electrolytic detachment mechanism with practice is both simple to use and reliable. The coils are however slightly stiffer than standard coils limiting their use in small aneurysms. This remains a technology in evolution.

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