A versatile approach to functionalized cyclic ketones bearing quaternary carbon stereocenters via organocatalytic asymmetric conjugate addition of nitroalkanes to cyclic β-substituted α,β-Enones

Tetrahedron ◽  
2021 ◽  
Vol 84 ◽  
pp. 132005
Author(s):  
Si-Jia Yu ◽  
Ya-Nan Zhu ◽  
Jian-Liang Ye ◽  
Pei-Qiang Huang
Keyword(s):  
Conjugate Addition ◽  
Quaternary Carbon ◽  
Cyclic Ketones

Asymmetric tandem conjugate addition–protonation to forge chiral secondary C–O bonds for quaternary carbon stereocenters at the nonadjacent β-position

2017 ◽  
Vol 53 (54) ◽  
pp. 7493-7496 ◽  
Author(s):  
San-Ni Hong ◽  
Yang Liu ◽  
Richmond Lee ◽  
Zhiyong Jiang
Keyword(s):  
Conjugate Addition ◽  
Quaternary Carbon ◽  
Efficient Approach

The first asymmetric tandem conjugate addition–protonation to methylene 1,3-oxazolidine-2,4-diones has been developed, thus providing a direct and efficient approach to assemble chiral secondary C–O bonds for quaternary carbon stereocenters and thiols at the nonadjacent β-position.

Stereoselective formation of tertiary and quaternary carbon centers via inverse conjugate addition of carbonucleophiles to allenic esters

Tetrahedron ◽  
2010 ◽  
Vol 66 (39) ◽  
pp. 7720-7725 ◽  
Author(s):  
Ana Lúcia Cardoso ◽  
Ana Matos Beja ◽  
Manuela Ramos Silva ◽  
Jesús M. de los Santos ◽  
Francisco Palacios ◽  
...  
Keyword(s):  
Conjugate Addition ◽  
Quaternary Carbon ◽  
Carbon Centers ◽  
Allenic Esters

Enantioselective Copper-Catalyzed Conjugate Addition to 2- or 3-Substituted Cyclopent-2-en-1-ones: Construction of Stereogenic Quaternary Carbon Centers

Synlett ◽  
2007 ◽  
Vol 2007 (13) ◽  
pp. 2057-2060 ◽  
Author(s):  
Alexandre Alexakis ◽  
Magali Vuagnoux-d’Augustin ◽  
Stefan Kehrli
Keyword(s):  
Conjugate Addition ◽  
Quaternary Carbon ◽  
Carbon Centers

Creation of Quaternary Stereogenic Centers via Copper-Catalyzed Asymmetric Conjugate Addition of Alkenyl Alanes to α,β-Unsaturated Cyclic Ketones

Synlett ◽  
2010 ◽  
Vol 2010 (11) ◽  
pp. 1694-1698 ◽  
Author(s):  
Alexandre Alexakis ◽  
Daniel Müller ◽  
Christine Hawner ◽  
Matthieu Tissot ◽  
Laëtitia Palais
Keyword(s):  
Conjugate Addition ◽  
Cyclic Ketones ◽  
Stereogenic Centers ◽  
Quaternary Stereogenic Centers
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