Green synthesis of diaryl selenides from arylboronic acids and arylseleninic acids.

A new method of deborylative selanylation using arylboronic acids and arylseleninic acids gave diaryl selenoethers and diarylselenoxide. The present approach requires only equimolar arylseleninic acid and led selectively to selenoethers or selenoxides depending on the solvent. The method is metal-free, base- or oxidant-free, efficient, and environmentally friendly.

Rh-Catalyzed Diastereoselective Addition of Arylboronic Acids to α-Keto N-tert-Butanesulfinyl Aldimines: Synthesis of α-Amino Ketones

Herein we present a diastereoselective addition of arylboronic acids to α-keto N-tert-butanesulfinyl aldimines catalyzed by Rh(I) catalyst. This reaction provides a practical method to deliver valuable chiral α-amino ketones with...

Cu/Fe-Mediated N(sp2)-arylation/alkenylation of pyridines with aryl-/alkenylboronic acids to yield versatile cationic materials

Cu/Fe-mediated arylation of pyridines with arylboronic acids, featuring low-cost catalytic system and easy operation, is disclosed. A series of length-controllable linear (the number of aryls ranges from 2 to 6)...

Diazaborines Oxidize Slowly with H2O2 but Rapidly with Peroxynitrite in Aqueous Buffer

Reactive oxygen species (ROS) such as H2O2 and peroxynitrite (ONOO-) oxidize arylboronic acids to their corresponding phenols. When used in molecular imaging probes and in ROS-responsive molecules, however, simple arylboronic...

Ni(II)-Catalyzed Intermolecular Selective Heck-Type Arylation of Unactivated Alkenes with Arylboronic Acids

The Ni(II)-catalyzed intermolecular arylation of unactivated alkenes with arylboronic acids has been disclosed for the first time. This alkene arylation exhibits excellent E/Z selectivity and regioselectivity (γ-selectivity) to provide the...

Synthesis of Novel 2-diethylamino-4H-7-(Het) aryl pyrido[1,2-a][1,3,5]triazin-4-ones via a Suzuki Cross-Coupling Reaction of 2-Diethylamino-4H-7-iodopyrido[1,2a][1,3,5]triazin-4-one with (Het) arylboronic Acids in Water

Suzuki cross coupling reaction is one of the most famous organic reactions of the 20th century’s chemistry. It is deemed of as one of the most famous reaction in the field of chemistry. It is a very effective method for making carbon–carbon bonds. It has been extensively utilized in the synthesis of many carbon molecules including the most complex ones.Syntheses of 2-diethylamino-4H-7-(Het) aryl pyrido [1,2-a] [1,3,5] triazin-4-ones are currently under investigation in order to obtain great potentialities in medicinal chemistry of compounds class. The methodology we propose herein is able to produce numerous 2-diethylamino-4H-7-(Het)arylpyrido[1,2-a][1,3,5]triazin-4-one and derivatives that were synthesized, purified and characterized by 1HNMR, 13CNMR, MS techniques. Furthermore, it allows sequential introduction of various substituents into a 2-alkylylamino-4H-7-(Het)arylpyrido[1,2-a][1,3,5]triazin-4-ones ring using a one-pot procedure. The biological evaluation as well as the physico-chemical characterisation of various products are currently under way and will be described elsewhere.