The reaction of (N-isocyanimino)triphenylphosphorane with dialkyl acetylenedicarboxylates in the presence of 1,3-diphenyl-1,3-propanedione: a novel three-component reaction for the stereoselective synthesis of dialkyl (Z)-2-(5,7-diphenyl-1,3,4-oxadiazepin-2-yl)-2-butenedioates

2007 ◽  
Vol 48 (14) ◽  
pp. 2617-2620 ◽  
Author(s):  
Ali Souldozi ◽  
Ali Ramazani ◽  
Nouri Bouslimani ◽  
Richard Welter
Keyword(s):  
Stereoselective Synthesis ◽  
Dialkyl Acetylenedicarboxylates ◽  
Three Component Reaction

Stereoselective synthesis of 3-[2-(dialkoxyphosphoryl)-1,2-dialkoxycarbonyl-ethyl]-4-hydroxycoumarins by reaction between trialkyl phosphites, dialkyl acetylenedicarboxylates and 4-hydroxycoumarin

2009 ◽  
Vol 2009 (5) ◽  
pp. 319-321 ◽  
Author(s):  
Mohammad Anary-Abbasinejad ◽  
Khadijeh Charkhati ◽  
Alireza Hassanabadi
Keyword(s):  
Stereoselective Synthesis ◽  
Dialkyl Acetylenedicarboxylates ◽  
Three Component Reaction ◽  
Trialkyl Phosphites ◽  
Efficient Route ◽  
High Yields

A three-component reaction between trialkyl phosphites, dialkyl acetylenedicarboxylates and 4-hydroxycoumarin is described as a simple and efficient route for the synthesis of 3-[2-(dialkoxyphosphoryl)-1,2-dialkoxycarbonyl-ethyl]-4-hydroxycoumarins in high yields.

ChemInform Abstract: Three-Component Reaction Between Alkyl(aryl) Isocyanides and Dialkyl Acetylenedicarboxylates in the Presence of Ethyl Trifluoroacetate.

ChemInform ◽  
2011 ◽  
Vol 42 (40) ◽  
pp. no-no
Author(s):  
Khatereh Khandan-Barani ◽  
Malek Taher Maghsoodlou ◽  
Sayyed Mostafa Habibi-Khorasani ◽  
Nourallah Hazeri ◽  
Seyyed Sajad Sajadikhah
Keyword(s):  
Alkyl Aryl ◽  
Dialkyl Acetylenedicarboxylates ◽  
Three Component Reaction

Nucleophilic Phosphine-Promoted Domino Reaction of Dialkyl Acetylenedicarboxylates and 3-Arylamino-1-methyl-1H-pyrrole-2,5-diones

Synthesis ◽  
2018 ◽  
Vol 50 (18) ◽  
pp. 3715-3722 ◽  
Author(s):  
Ying Han ◽  
Chao-Guo Yan ◽  
Chang-Zhou Liu ◽  
Yuan-Yuan Zhang ◽  
Jing Sun
Keyword(s):  
Room Temperature ◽  
Domino Reaction ◽  
Dimethyl Acetylenedicarboxylate ◽  
Dialkyl Acetylenedicarboxylates ◽  
Three Component Reaction

The three-component reaction of triphenylphosphine, dimethyl acetylenedicarboxylate and 3-arylamino-1-methyl-1H-pyrrole-2,5-diones in CH2Cl2 at room temperature resulted in functionalized 3-(triphenyl-λ5-phosphanylidene)succinates in nearly quantitative yields. However, tri(n-butyl)phosphine promoted reaction of dialkyl acetylenedicarboxylates and 3-arylamino-1-methyl-1H-pyrrole-2,5-diones in CH2Cl2 afforded functionalized pyrrolo[3,4-b]pyridine-4-carboxylates in satisfactory yields.

An efficient one-pot stereoselective synthesis of 2,6-disubstituted 4-thiocyanatotetrahydropyrans

2021 ◽  
Vol 08 ◽  
Author(s):  
Chithaluri Sudhakar ◽  
Pochamoni Ramudu
Keyword(s):  
Room Temperature ◽  
Stereoselective Synthesis ◽  
One Pot ◽  
Three Component Reaction

: An efficient stereoselective synthesis of 2,6-disubstituted-4-thiocyanatotetrahydropyrans has been developed through a one pot three-component reaction of aldehydes, trimethyl allylsilane and NH4SCN in the presence of BF3.Et2O at room temperature. The products are formed rapidly (10-30 min) in excellent yields (78-98%).

scholarly journals A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction

2012 ◽  
Vol 9 (4) ◽  
pp. 2239-2244 ◽  
Author(s):  
Hossein Anaraki-Ardakani ◽  
Maziar Noei ◽  
Mina Karbalaei-Harofteh ◽  
Shahab Zomorodbakhsh
Keyword(s):  
Room Temperature ◽  
Facile Synthesis ◽  
One Pot ◽  
Pyrrole Derivatives ◽  
Dialkyl Acetylenedicarboxylates ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields ◽  
Neutral Conditions

A new and efficient one-pot synthesis of polysubstituted pyrrole derivatives by three-component reaction between dialkyl acetylenedicarboxylates, triphenylphosphine, 2-aminopyridin derivatives in the presence of arylglyoxals is described. The reactions were performed in dichloromethane at room temperature and neutral conditions and afforded high yields of products.

scholarly journals Unexpected isocyanide-based three-component bicyclization for the stereoselective synthesis of densely functionalized pyrano[3,4-c]pyrroles

2016 ◽  
Vol 52 (5) ◽  
pp. 900-903 ◽  
Author(s):  
Qian Gao ◽  
Wen-Juan Hao ◽  
Feng Liu ◽  
Shu-Jiang Tu ◽  
Shu-Liang Wang ◽  
...  
Keyword(s):  
Stereoselective Synthesis ◽  
Efficient Synthesis ◽  
Dialkyl Acetylenedicarboxylates

A novel three-component bicyclization strategy for the efficient synthesis of densely functionalized pyrano[3,4-c]pyrroles has been established from readily accessible 3-aroylacrylic acids, dialkyl acetylenedicarboxylates and isocyanides.

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