Unexpected solvent/substitution-dependent inversion of the enantioselectivity in Michael addition reaction using chiral phase transfer catalysts

2015 ◽  
Vol 56 (37) ◽  
pp. 5209-5212 ◽  
Author(s):  
Ponmuthu Kottala Vijaya ◽  
Sepperumal Murugesan ◽  
Ayyanar Siva
Keyword(s):  
Michael Addition ◽  
Phase Transfer ◽  
Addition Reaction ◽  
Michael Addition Reaction ◽  
Chiral Phase ◽  
Phase Transfer Catalysts ◽  
Chiral Phase Transfer Catalysts ◽  
Solvent Substitution

ChemInform Abstract: Highly Enantioselective Michael Addition Reactions with New Trimeric Chiral Phase Transfer Catalysts.

ChemInform ◽  
2015 ◽  
Vol 46 (33) ◽  
pp. no-no
Author(s):  
Arockiam Jesin Beneto ◽  
Jayaraman Sivamani ◽  
Veeramanoharan Ashokkumar ◽  
Rajendiran Balasaravanan ◽  
Kumaraguru Duraimurugan ◽  
...  
Keyword(s):  
Michael Addition ◽  
Phase Transfer ◽  
Addition Reactions ◽  
Chiral Phase ◽  
Phase Transfer Catalysts ◽  
Chiral Phase Transfer Catalysts

Highly enantioselective Michael addition reactions with new trimeric chiral phase transfer catalysts

2015 ◽  
Vol 39 (4) ◽  
pp. 3098-3104 ◽  
Author(s):  
Arockiam Jesin Beneto ◽  
Jayaraman Sivamani ◽  
Veeramanoharan Ashokkumar ◽  
Rajendiran Balasaravanan ◽  
Kumaraguru Duraimurugan ◽  
...  
Keyword(s):  
Michael Addition ◽  
Quaternary Ammonium ◽  
Phase Transfer ◽  
Quaternary Ammonium Salts ◽  
Ammonium Salts ◽  
Addition Reactions ◽  
Chiral Phase ◽  
Catalytic Activities ◽  
Phase Transfer Catalysts ◽  
Chiral Phase Transfer Catalysts

New types of mesitylene based tri-site containing asymmetric quaternary ammonium salts 9 (9a and 9b) were synthesized and their catalytic activities were studied using Michael addition reactions with various chalcones and diethylmalonate under mild basic conditions with very good yields and ee's.

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