Toxicological investigations, including hair testing, in a death involving gabapentin

Author(s):  
Alice Ameline ◽  
Audrey Farrugia ◽  
Jean-Sébastien Raul ◽  
Pascal Kintz
Keyword(s):  
2005 ◽  
Vol 35 (18) ◽  
pp. 45
Author(s):  
GIDEON KOREN
Keyword(s):  

2017 ◽  
Vol 48 ◽  
pp. 91-98 ◽  
Author(s):  
Joseph J. Palamar ◽  
Alberto Salomone ◽  
Enrico Gerace ◽  
Daniele Di Corcia ◽  
Marco Vincenti ◽  
...  

2020 ◽  
pp. 69-93
Author(s):  
Edward J. Cone ◽  
Robert E. Joseph
Keyword(s):  

2002 ◽  
Vol 1 (1) ◽  
pp. 86-101 ◽  
Author(s):  
Jason Ditton

Extensive forensic examination of the hair of 209 'Ecstasy' (MDMA) users demonstrated virtually no correlation between self-reported tablet use, and traces of MDMA in the hair of users. Why should this be so? Three answers are possible, and all true. First, self-report is fallible; second, tablet strength varies enormously; and third, forensic analysis is of unknown accuracy. The first two are well known. Forensic analysis, however, typically presents itself as impeccably precise. The article demonstrates that not only is this claim spectacularly untrue, but also that validation of forensic analysis (and, thus, indirectly, self-report) lies in the very blind intra- and inter- laboratory comparisons that are never undertaken.


2020 ◽  
pp. 95-120
Author(s):  
Manfred R. Moeller ◽  
Hans P. Eser

2019 ◽  
Vol 38 (1) ◽  
pp. 277-286 ◽  
Author(s):  
Islam Amine Larabi ◽  
Marie Martin ◽  
Nicolas Fabresse ◽  
Isabelle Etting ◽  
Yve Edel ◽  
...  

Abstract Purpose To demonstrate the usefulness of hair testing to determine exposure pattern to fentanyls. Methods A 43-year-old male was found unconscious with respiratory depression 15 min after snorting 3 mg of a powder labeled as butyrylfentanyl. He was discharged from hospital within 2 days without blood or urine testing. Two locks of hair were sampled 1 month (M1 A: 0–2 cm (overdose time frame); B: 2–4 cm; C: 4–6 cm) and 1 year (Y1: A: 0–2 cm; B: 2–4 cm) later to monitor his exposure to drugs of abuse by liquid chromatography–tandem mass spectrometry after liquid-liquid extraction. Results Hair analysis at M1 showed a repetitive exposure to 3-fluorofentanyl (A/B/C: 150/80/60 pg/mg) with higher concentration in segment A reflecting the overdose period. The non-detection of butyrylfentanyl was consistent with the analysis of the recovered powder identified as 3-fluorofentanyl. Furanylfentanyl (40/20/15 pg/mg) and fentanyl (37/25/3 pg/mg) were also detected in hair. The second hair analysis at Y1 showed the use of three new fentanyls, with probably repetitive exposures to methoxyacetylfentanyl (A/B: 500/600 pg/mg), and single or few exposures to carfentanil (2.5/3 pg/mg) and acetyl fentanyl (1/1 pg/mg). A decreasing exposure to 3-fluorofentanyl (25/80 pg/mg), and increasing consumption of furanylfentanyl (310/500 pg/mg) and fentanyl (620/760 pg/mg) were also observed despite methadone treatment initiation. The patient claimed not consuming three out of the six detected fentanyls. Conclusions We report single or repetitive exposure to several fentanyls using hair testing. To our knowledge, this is the first demonstration of 3-fluorofentanyl and methoxyacetylfentanyl in hair samples collected from an authentic abuser.


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